Author

S. J. Loo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Organism:plant (other)· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

A. Prakash· 1 shared C. J. Ramachandra· 1 shared C. Tan· 1 shared D. J. Hausenloy· 1 shared D. Offen· 1 shared E. G. Petretto· 1 shared E. Lim· 1 shared E. P. Yap· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPhysiology

A. Prakash

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2 papers

Recent·Most cited

The DJ-1-derived peptide, ND-13, confers cardioprotection by inhibiting mitochondrial fission and preserving mitochondrial bioenergetics via the RhoA-ROCK1-Drp1 pathway

A. Prakash, G. E. Crespo-Avilan, S. J. Loo, E. P. Yap, J. Chua, J. Ching, Z. Yitong, Y.-H. Lin, W. Contreras, F. Yu, S. Cong, L. C. Dam, C. J. Ramachandra, S. B. Kalkhoran, S. Lu, , D. J. Hausenloy

This study shows that the DJ-1-derived peptide ND-13 reduces myocardial infarct size and preserves cardiac function by inhibiting mitochondrial fission and improving mitochondrial bioenergetics through the RhoA-ROCK1-Drp1 pathway.

bioRxiv · Jun 24, 2024 · PreprintPhysiology

PLURIPOTENT STEM CELL-DERIVED CARDIOVASCULAR PROGENITORS DIFFFERENTIATED ON LAMININ 221 REGENERATE AND IMPROVE FUNCTION OF INFARCTED SWINE HEARTS

L. Yap, L. Y. Chong, C. Tan, S. Adusumalli, M. Seow, J. Guo, Z. Cai, S. J. Loo, E. Lim, N. Lath, L. Ye, E. G. Petretto, K. Tryggvason

This paper differentiates pluripotent stem cells into cardiovascular progenitors on laminin 221 and shows improved heart function in infarcted pigs.

bioRxiv · Apr 29, 2021 · PreprintCell Biology