Author

S. N. Floor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Frost· 1 shared A. G. Myasnikov· 1 shared A. Palla· 1 shared A. Sil· 1 shared A. Subramanian· 1 shared D. Galonic Fujimori· 1 shared D. Hockemeyer· 1 shared D. L. Swaney· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

A. Frost

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Author profile →

3 papers

Recent·Most cited

Cell BiologybioRxivJun 10, 2022

A Legionella toxin mimics tRNA and glycosylates the translation machinery to trigger a ribotoxic stress response.

A. Subramanian, L. Wang, T. Moss…·S. Mukherjee

This paper identifies SidI, a Legionella toxin that mimics tRNA, glycosylates the translation machinery, and triggers a ribotoxic stress response leading to cell death.

DOI 10.1038/s41556-023-01248-z

humanproteomics

𝕏 PostBluesky

BiochemistrybioRxivMar 12, 2021

Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance

K. Tsai, V. Stojkovic, L. Noda-Garcia…·D. Galonic Fujimori

This study uses directed evolution to identify Cfr variants that enhance rRNA methylation, revealing structural insights into antibiotic resistance mechanisms.

DOI 10.7554/elife.70017

structural biologyexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivJun 26, 2017

Widespread translational remodeling during human neuronal differentiation

J. D. Blair, D. Hockemeyer, J. A. Doudna…·S. N. Floor

The paper investigates translational changes during human neuronal differentiation and identifies mTOR complex 1 signaling and 3' UTR regulation as key factors.

DOI 10.1016/j.celrep.2017.10.095

humanbulk RNA-seq

𝕏 PostBluesky