S. P. Hunger

The paper identifies lncRNA regulatory networks in pediatric cancers using integrated genomics data from 1,044 samples, revealing their roles in proliferation, metabolism, and DNA damage.

This study uses single-cell multi-omics to identify lineage plasticity and stem-cell-like blasts in KMT2A-rearranged leukemia, linking these features to poor prognosis in infants.

The paper identifies a germline non-coding GATA3 variant that alters chromatin topology and contributes to Ph-like ALL by activating an enhancer and reshaping 3D genome organization.

This study identifies and characterizes noncoding mutations in pediatric cancers using a computational framework and experimental validation, revealing their role in deregulating cis-regulatory landscapes.