Author

S. Pfeiler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Organism:human· 1

Frequent Co-Authors

N. Gerdes· 5 shared M. Kelm· 4 shared A. Lang· 2 shared C. Elster· 2 shared H. Winkels· 2 shared T. Vajen· 2 shared U. Floegel· 2 shared A. Beele· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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5 shared papersImmunology

N. Gerdes

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Crosstalk between thrombospondin-1 and CD36 modulates platelet-RBC interaction limiting thrombosis and abdominal aneurysm formation

K. J. Krott, T. Feige, A. Bosbach, A. Beele, I. Krueger, F. Reusswig, E. Schickentanz-Dey, A. Chadt, M. Kelm, N. Gerdes, S. Pfeiler, K. Jurk, K. Kiouptsi, C. Reinhardt, H. Al-Hasani, , M. Elvers

This study identifies a novel CD36-TSP-1 signaling pathway that modulates platelet-RBC interaction, promoting thrombus formation and contributing to abdominal aortic aneurysm pathology.

bioRxiv · Mar 18, 2024 · PreprintPathology

Using TCR and BCR sequencing to unravel the role of T and B cells in abdominal aortic aneurysm

C. Elster, M. Ommer-Bläsius, A. Lang, T. Vajen, S. Pfeiler, M. Feige, K. Le Quy, M. Chernigovskaya, M. Kelm, H. Winkels, S. V. Schmidt, V. Greiff, N. Gerdes

This study uses scRNA TCR and BCR sequencing to analyze T and B cell responses in murine AAA, finding no clonal expansion of TCRs or BCRs.

Frontiers in Cardiovascular Medicine · Nov 14, 2023Peer-reviewedImmunology

Inhibition of CD40-TRAF6 signaling protects against aneurysm development and progression

M. Ommer-Blaesius, T. Vajen, C. Elster, S. Verheyen, S. Pfeiler, C. Quast, J. Odendahl, A. Lang, E. Lutgens, M. Kelm, N. Gerdes

This study shows that inhibiting CD40-TRAF6 signaling reduces abdominal aortic aneurysm severity and progression in mice.

bioRxiv · Mar 24, 2023 · PreprintPharmacology & Toxicology

Quantitative assessment of angioplasty induced vascular inflammation with 19F cardiovascular magnetic resonance imaging

F. Nienhaus, M. Walz, M. Rothe, A. Jahn, S. Pfeiler, H. L. Busch, M. Stern, C. Heiss, L. Vornholz, S. Cames, M. Cramer, V. Schrauwen-Hinderling, N. Gerdes, S. Temme, M. Roden, , F. Boenner

This study uses 19F MRI to quantify monocyte/macrophage infiltration after vascular injury with sufficient sensitivity.

bioRxiv · Nov 25, 2022 · PreprintImmunology

Inhibition of myeloperoxidase prevents thoracic aortic aneurysm formation in Marfan mice

D. Mehrkens, F. S. Nettersheim, F. Ballmann, J. Bastigkeit, A. Brueckner, J. Dohr, S. Geissen, L. De Vore, P. Schelemei, F. R. Picard, M. Kochen, S. Braumann, W. Kreuzberg, A. Hof, H. Guthoff, , H. Winkels

This study shows that inhibiting myeloperoxidase prevents thoracic aortic aneurysms in Marfan mice by reducing inflammation and extracellular matrix damage.

bioRxiv · Nov 24, 2022 · PreprintImmunology