Author

S. V. Schmidt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

E. Latz· 2 shared A. Dernst· 1 shared A. Jaensch· 1 shared A. Lang· 1 shared A. Wagener· 1 shared B. Martin· 1 shared B. S. Franklin· 1 shared C. Budden· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

E. Latz

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Butyrate and propionate are microbial danger signals that activate the NLRP3-inflammasome in human macrophages in the presence of TLR stimulation

W. Wang, A. Dernst, B. Martin, L. Lorenzi, K. Phulphagar, A. Wagener, C. Budden, N. Stair, T. Wagner, H. Faerber, A. Jaensch, R. Stahl, F. Duthie, S. V. Schmidt, R. C. Coll, , E. Latz

The paper shows that butyrate and propionate activate the NLRP3 inflammasome in human macrophages when combined with TLR agonists, through HDAC inhibition and epigenetic changes.

bioRxiv · Mar 26, 2024 · PreprintImmunology

Using TCR and BCR sequencing to unravel the role of T and B cells in abdominal aortic aneurysm

C. Elster, M. Ommer-Bläsius, A. Lang, T. Vajen, S. Pfeiler, M. Feige, K. Le Quy, M. Chernigovskaya, M. Kelm, H. Winkels, S. V. Schmidt, V. Greiff, N. Gerdes

This study uses scRNA TCR and BCR sequencing to analyze T and B cell responses in murine AAA, finding no clonal expansion of TCRs or BCRs.

Frontiers in Cardiovascular Medicine · Nov 14, 2023Peer-reviewedImmunology

PI 3-kinase isoform p110α mediated FOXO1 inactivation protects against aortic aneurysm formation

M. Vantler, M. Schorscher, E. M. Berghausen, M. Zierden, J. Spitzer, J. B. Moore, D. Wong, Z. Li, M. Wissmueller, L. Gnatzy-Feik, D. Unnersjoe-Jess, L.-M. A. Zimmermann, M. Grandoch, D. Mehrkens, M. Adam, , S. Rosenkranz

This study shows that p110α-mediated FOXO1 inactivation in smooth muscle cells prevents aortic aneurysm formation by maintaining vascular homeostasis and promoting reparative SMC phenotypes.

bioRxiv · Dec 1, 2022 · PreprintCell Biology

Platelets fuel the inflammasome activation of innate immune cells

V. Rolfes, L. S. Ribeiro, I. Hawwari, L. Buotcher, N. S. Rosero, S. Maasewerd, M. L. S. Santos, S. V. Schmidt, M. Rothe, J. Stunden, L. H. Carvalho, C. J. Fontes, T. Prochnicki, M. Arditi, E. Latz, B. S. Franklin

This study shows platelets enhance inflammasome activation in immune cells, increasing IL-1β production, and identifies a platelet gene signature linked to autoinflammatory diseases.

bioRxiv · Oct 11, 2019Immunology