S. Ramirez

Psychedelics Relax Priors and Reshape Orbitofrontal Dynamics

This study tests the REBUS model of psychedelics by showing they slow decision times, improve accuracy, and reduce top-down influence in mice.

Multi-Niche Human Bone Marrow On-A-Chip for Studying the Interactions of Adoptive CAR-T Cell Therapies with Multiple Myeloma

This study develops a 3D bone marrow-on-a-chip model to investigate interactions between CAR-T cells and multiple myeloma cells in different niches and assess therapeutic responses.

Chronic Gq activation of ventral hippocampal neurons and astrocytes differentially affects memory and behavior

This study shows that chronic activation of Gq pathways in hippocampal neurons and astrocytes differentially affects memory, anxiety, and social behaviors, with distinct impacts on microglia.

Nirmatrelvir Resistant SARS-CoV-2 Variants with High Fitness in Vitro

This study identifies nirmatrelvir-resistant SARS-CoV-2 variants with high in vitro fitness and shows that remdesivir remains effective against them.

Population-specific patterns of toxin sequestration in monarch butterflies from around the world

This study examines genetic variation in toxin sequestration in monarch butterflies across populations and host species, finding reduced sequestration in some populations under different ecological conditions.

Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 in Vitro

This study evaluates the efficacy of HCV protease inhibitors against SARS-CoV-2 and their interactions with remdesivir, finding simeprevir shows synergism and is the most promising for future antiviral treatments.

In vitro efficacy of Artemisinin-based treatments against SARS-CoV-2

This study evaluates the in vitro antiviral efficacy of Artemisia annua extracts and artemisinin derivatives against SARS-CoV-2, finding artesunate to be the most potent.

Efficient culture of SARS-CoV-2 in human hepatoma cells enhances viability of the virus in human lung cancer cell lines permitting the screening of antiviral compounds

This paper adapts SARS-CoV-2 to replicate more efficiently in human cells, enabling antiviral compound screening across multiple cell lines.

Comparative of probiotics reveals cecal microbial component associated with performance parameters in broilers

This study evaluates the effects of different probiotics on cecal microbial communities and performance in broilers, finding that specific formulations improve growth and reduce mortality.

Comparative effectiveness of probiotic-based formulations on cecal microbiota modulation in broilers

This study evaluates five probiotic formulations' effects on cecal microbiota in broilers at 21 and 42 days, finding varied microbial modulation with no overall diversity differences by 42 days.