Author

S. Shetty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cancer Biology· 1 Cell Biology· 1 Immunology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 6 Research Focus:cell type annotation· 5 Research Focus:differential expression· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3

Frequent Co-Authors

A. C. Meyer-Gerspach· 1 shared A. Kiraly· 1 shared A. Sedgwick· 1 shared A. Suarez-Arnedo· 1 shared A. Thomas· 1 shared B. K. Wölnerhanssen· 1 shared C. Guo· 1 shared C. Landaverde· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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1 shared paperPhysiology

A. C. Meyer-Gerspach

Mutual co-authors in cluster

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8 papers

Recent·Most cited

Synthetic Hydrogels with Entangled Neutrophil Extracellular Traps Influence Tumor Progression in MDA-MB-231 Cells

R. Katz, S. Shetty, J. L. West

This study shows that synthetic hydrogels containing neutrophil extracellular traps (NETs) promote survival, proliferation, and metastatic traits in TNBC cells, with IL-8 mediating NETosis.

bioRxiv · Sep 27, 2023 · PreprintBioengineering

A balance between pro-inflammatory and pro-reparative macrophages is observed in regenerative D-MAPS

Y. Liu, A. Suarez-Arnedo, S. Shetty, M. Schneider, J. H. Collier, T. Segura, Y. Wu

The paper investigates the immunomodulatory effect of D-MAPS and finds a balance between pro-inflammatory and pro-reparative macrophages in regenerative scaffolds.

bioRxiv · Aug 17, 2022Bioengineering

Exploring the prognostic value of SCARF1 in non-small cell lung cancers

D. A. Patten, S. Shetty

This study investigates SCARF1 expression in lung cancers, finding it correlates with immune infiltration and prognosis in lung adenocarcinoma but not in lung squamous cell carcinoma.

bioRxiv · Jan 28, 2021 · PreprintCancer Biology

Exosome-Mediated mRNA Delivery For SARS-CoV-2 Vaccination

S. J. Tsai, C. Guo, A. Sedgwick, S. Kanagavelu, J. Nice, S. Shetty, C. Landaverde, N. A. Atai, S. J. Gould

This paper develops exosome-based mRNA vaccines that express SARS-CoV-2 antigens, showing long-lasting immune responses and fewer adverse effects than lipid nanoparticles.

bioRxiv · Nov 6, 2020 · PreprintImmunology

Diet-induced loss of adipose Hexokinase 2 triggers hyperglycemia

M. Shimobayashi, S. Shetty, I. C. Frei, B. K. Wölnerhanssen, D. Weissenberger, N. Dietz, A. Thomas, D. Ritz, A. C. Meyer-Gerspach, T. Maier, N. Hay, R. Peterli, N. Rohner, M. N. Hall

The paper shows that loss of Hexokinase 2 in adipose tissue due to high fat diet leads to hyperglycemia through systemic glucose homeostasis disruption.

bioRxiv · Dec 28, 2019Physiology

Effect of temperature and agitation rate variation on the growth of NS0 cell line in monoclonal antibody production

S. Shetty

This study examines how temperature and agitation rate affect NS0 cell growth and monoclonal antibody production, finding that temperature has a greater impact than agitation rate.

bioRxiv · Oct 29, 2019 · PreprintCell Biology

Predicting Brain Age Using Structural Neuroimaging and Deep Learning

Y. Varatharajah, S. Baradwaj, A. Kiraly, D. Ardila, R. Iyer, S. Shetty, K. Kohlhoff

This paper develops deep learning models to predict brain age from structural MRI data and finds that predicted brain age differs between cognitively impaired and healthy individuals of similar chronological age.

bioRxiv · Dec 17, 2018 · PreprintBioengineering

Gut microbiota features of the geographically diverse Indian population

S. Shetty

This study profiles the gut microbiota of over 1000 Indians across 14 cities, finding geographic variation and Prevotella dominance, with high Treponema prevalence despite western lifestyle trends.

bioRxiv · Nov 27, 2018 · PreprintMicrobiology