S. X. Sun

This study identifies a mechanism where cytoskeletal activation of NHE1 drives secondary volume increase and affects cell proliferation in response to hypotonic stress.

The paper identifies Polyaneuploid Cancer Cells (PACCs) as metastasis-competent cells through increased motility, elasticity, and survival in circulation.

The paper develops a computational model of cell growth and proteome increase to explain the correlation between cell and nuclear volume, showing that transport rates and ribosome dynamics influence growth and volume ratios.

This study uses a microfluidic platform to show renal epithelial cells generate hydraulic pressure gradients, with PKD cells showing reversed fluid flow and higher stall pressure.

The paper develops a theoretical model showing how cell migration transitions from actin-driven to water-driven mechanisms based on environmental constraints.

This study investigates how cell volume in non-excitable tissue cells is regulated by membrane potential and ion concentrations, showing volume changes under different conditions.

The paper demonstrates that membrane tension-sensitive calcium currents and ion channels regulate Rho GTPase and myosin contraction, and that YAP translocates in response to mechanical compression.