Author

T. Froehlich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell-cell communication· 2 Organism:plant (other)· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Baehr· 2 shared A. Scholz· 2 shared B. Macek· 2 shared B. Shashikadze· 2 shared C. Kupatt· 2 shared E. Wolf· 2 shared F. O. Fagbadebo· 2 shared M. Stirm· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

A. Baehr

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Nanobodies as novel tools to monitor the mitochondrial fission factor Drp1

T. Froehlich, A. Jenner, C. Cavarischia-Rega, F. O. Fagbadebo, Y. Lurz, D. I. Frecot, P. D. Kaiser, S. Nueske, A. Scholz, E. Schaeffer, A. J. Garcia-Saez, B. Macek, U. Rothbauer

This study develops nanobodies to monitor Drp1, a mitochondrial fission factor, using proteomics, microscopy, and live-cell imaging techniques to study its dynamics in disease models.

bioRxiv · Dec 18, 2023 · PreprintCell Biology

Increased pulmonary monocyte infiltration and attenuated phagocytosis defines perinatal dysfunction of innate immunity in Cystic Fibrosis

F. Jaudas, F. Bartenschlager, B. Shashikadze, G. Santamaria, A. Schnell, N. Naumann-Barsch, H. Bruns, S. Y. Graeber, A. Baehr, M. Cambra-Bort, M. Stirm, J. B. Stoeckl, S. Krebs, H. Blum, C. Schulz, , N. Klymiuk

The paper identifies increased monocyte infiltration and reduced phagocytosis in CF lungs at birth, suggesting innate immune dysfunction and the need for early treatment.

bioRxiv · Sep 11, 2023 · PreprintImmunology

A nanobody-based toolset to monitor and modify the mitochondrial GTPase Miro1

F. O. Fagbadebo, P. D. Kaiser, K. Zittlau, N. Bartlick, T. R. Wagner, T. Froehlich, G. Jarjour, S. Nueske, A. Scholz, B. Traenkle, B. Macek, U. Rothbauer

This study develops Miro1-specific nanobodies as tools for monitoring and modifying Miro1 function in cells, with applications in imaging and targeted degradation.

bioRxiv · Dec 10, 2021Cell Biology

A scalable, clinically severe pig model for Duchenne muscular dystrophy

M. Stirm, L. M. Fonteyne, B. Shashikadze, M. Lindner, M. Chirivi, A. Lange, C. Kaufhold, C. Mayer, I. Medugorac, B. Kessler, M. Kurome, V. Zakhartchenko, A. Hinrichs, E. Kemter, S. Krause, , E. Wolf

This paper develops a scalable pig model for Duchenne muscular dystrophy by breeding DMD carriers, enabling large cohorts for disease mechanism studies and therapeutic testing.

Disease Models & Mechanisms · Dec 1, 2021Peer-reviewedPathology