Author

T. Henriques

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:zebrafish· 1

Frequent Co-Authors

B. J. Abraham· 1 shared C. G. Ludwig· 1 shared C. Wu· 1 shared D. Liu· 1 shared K. Adelman· 1 shared K. Y. Chen· 1 shared L. I. Zon· 1 shared M. Geyer· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

B. J. Abraham

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1 paper

Recent·Most cited

CDK13 Mutations Drive Melanoma via Accumulation of Prematurely Terminated Transcripts

M. L. Insco, B. J. Abraham, S. J. Dubbury, S. Dust, C. Wu, K. Y. Chen, D. Liu, C. G. Ludwig, S. Bellaousov, T. Fabo, T. Henriques, K. Adelman, M. Geyer, P. A. Sharp, R. A. Young, , L. I. Zon

This study identifies CDK13 mutations in melanoma, showing they lead to accumulation of truncated transcripts and poor survival, with a mechanism involving impaired ZC3H14 phosphorylation and PAXT complex recruitment.

bioRxiv · Nov 5, 2019Biophysics