Author

T. Higgins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. B. Smith· 1 shared A. D. Claussen· 1 shared A. Finzi· 1 shared B. Mostaert· 1 shared C. Abrams· 1 shared D. Lee· 1 shared D. Nguyen· 1 shared G. Gendron-Lepage· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. B. Smith

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2 papers

Recent·Most cited

Piperidine CD4-mimetic compounds expose vulnerable Env epitopes sensitizing HIV-1-infected cells to ADCC

S. Ding, W. D. Tolbert, H. Zhu, D. Lee, T. Higgins, X. Zhao, D. Nguyen, R. Sherburn, J. Richard, G. Gendron-Lepage, H. Medjahed, M. Mohammadi, C. Abrams, M. Pazgier, A. B. Smith, A. Finzi

The paper describes piperidine-based CD4-mimetic compounds that expose HIV-1 Env epitopes, increasing sensitivity to ADCC by targeting Asp368.

bioRxiv · Mar 23, 2023 · PreprintImmunology

Cochlear implant material effects on inflammatory cell function and foreign body response

M. J. Jensen, A. D. Claussen, T. Higgins, R. Vielman-Quevado, B. Mostaert, L. Xu, J. Kirk, M. R. Hansen

This study examines how cochlear implant materials affect macrophage and fibroblast function and fibrous tissue growth, finding greater fibrosis and bone formation around platinum compared to PDMS.

bioRxiv · Jun 20, 2022Bioengineering