T. Izumi

This study compares HIV-1 virion maturation and infectivity between Jurkat and HEK293T cells using a FRET-based assay, finding lower maturation and infectivity in Jurkat-derived virions.

This paper identifies N4BP1 as a host factor that suppresses HBV replication by degrading HBV RNAs, with its KH-like and RNase domains required for this effect.

This study identifies four conserved cysteine residues in KSHV ORF34 essential for vPIC formation and viral production through alanine-scanning mutants and structural modeling.

The paper investigates the functional hierarchy of Rab27 effectors in insulin secretion by comparing exocytic phenotypes in beta cells lacking different combinations of effectors.

This study identifies miRNAs other than miR-122 that support HCV replication in non-hepatic cells by interacting with the viral 5UTR and stabilizing the IRES structure.

The paper develops a transgenic mouse model with GO-ATeam to measure ATP dynamics in real-time across multiple organs and conditions, providing insights into ATP's role in physiology and disease.

This study identifies ORF66's critical role in KSHV late gene expression and viral production by interacting with ORF34 and binding to the K8.1 promoter.

This study shows that actin cytoskeleton reorganization and non-protein molecules secreted by MC3T3-E1 cells regulate extracellular matrix mineralization during osteoblast differentiation.