Author

T. Kitaguchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

S. Arai· 2 shared S. R. Sarker· 2 shared A. Endo· 1 shared A. Kato· 1 shared A. Kidera· 1 shared A. Morita· 1 shared A. Teranishi· 1 shared B. Zhu· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiophysics

S. Arai

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

qMaLioffG: A single green fluorescent protein FLIM indicator enabling quantitative imaging of endogenous ATP

S. Arai, H. Itoh, C. Q. Vu, M. Nakayama, M. Oshima, A. Morita, K. Okamoto, S. Okuda, A. Teranishi, M. Osawa, Y. Tamura, S. Nonoyama, M. Takuma, T. Fujie, S. R. Sarker, , T. Kitaguchi

The paper introduces qMaLioffG, a green fluorescent protein FLIM indicator that quantitatively measures endogenous ATP levels by detecting fluorescence lifetime changes in physiological ATP concentrations.

bioRxiv · Aug 29, 2023 · PreprintBiophysics

Exocytotic dynamics of glucagon-like peptide-1 from enteroendocrine L cell line is regulated by actin polymerization

K. Harada, M. Takashima, T. Kitaguchi, T. TSUBOI

The paper investigates how actin polymerization regulates exocytosis of GLP-1 granules in mouse L cells after Ca2+ or cAMP elevation.

bioRxiv · Sep 14, 2022 · PreprintCell Biology

Creating a thermostable beta-glucuronidase switch for homogeneous immunoassay by disruption of conserved salt bridges at diagonal interfaces

B. Zhu, Q. Cheng, H. Tang, T. Kitaguchi, H. Ueda

This paper develops a thermostable beta-glucuronidase switch by disrupting salt bridges, enhancing signal-to-background ratio for immunosensors.

bioRxiv · May 19, 2022Bioengineering

Photothermal Dye-based Subcellular-sized Heat Spot Enabling the Modulation of Local Cellular Activities

F. Ferdinandus, M. Suzuki, Y. Harada, S. R. Sarker, S. i. Ishiwata, T. Kitaguchi, S. Arai

The paper introduces nanoHT, a photothermal nanoparticle that creates subcellular heat spots to modulate cellular activities, inducing cell death and muscle contraction in specific areas.

bioRxiv · Dec 19, 2021 · PreprintBioengineering

The molecular basis of ubiquitin-specific protease 8 autoinhibition by the WW-like domain

K. Kakihara, K. Asamizu, K. Moritsugu, M. Kubo, T. Kitaguchi, A. Endo, A. Kidera, M. Ikeguchi, A. Kato, M. Komada, T. Fukushima

This study identifies an autoinhibitory WW-like domain in USP8 that regulates its enzyme activity and links its release to Cushings disease.

bioRxiv · May 31, 2021Biochemistry