Author

T. Ptacek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:DNA methylation· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Nellore· 1 shared A. Rosal-Vela· 1 shared A. Rosenberg· 1 shared B. Mousseau· 1 shared C. D. Scharer· 1 shared C. Fan· 1 shared C. L. Ortiz· 1 shared C. Liao· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

A. Nellore

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ZHX2 Promotes HIF1α Oncogenic Signaling in Triple-Negative Breast Cancer

W. Fang, C. Liao, R. Shi, J. Simon, T. Ptacek, G. Zurlo, Y. Ye, L. Han, C. Fan, C. L. Ortiz, H.-R. Lin, U. Manocha, W. Luo, W. Y. Kim, L.-W. Yang, Q. Zhang

This study identifies ZHX2 as a promoter of HIF1α oncogenic signaling in TNBC, showing its role in cell growth, invasion, and metastasis through interaction with HIF1.

bioRxiv · May 27, 2021Cancer Biology

IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation

E. Zumaquero, S. L. Stone, C. D. Scharer, S. A. Jenks, A. Nellore, B. Mousseau, A. Rosal-Vela, D. Botta, J. E. Bradley, W. Wojciechowski, T. Ptacek, M. I. Danila, J. C. Edberg, S. L. Bridges, R. P. Kimberly, , F. E. Lund

This study shows IFNγ promotes T-bet expressing B cell differentiation and epigenetic reprogramming in humans, enhancing IL-21-driven antibody production.

bioRxiv · Feb 21, 2019Immunology