Author

L.-W. Yang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 3 Approach:experimental assay· 2 Approach:mechanistic / dynamical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

H.-R. Lin· 3 shared Y.-Y. Chang· 2 shared A. Kitao· 1 shared B.-C. Huang· 1 shared C. Fan· 1 shared C. L. Ortiz· 1 shared C. Liao· 1 shared C.-C. Wu· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersCell Biology

H.-R. Lin

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Computer simulations reveal pathogenicity and inheritance modes of hearing loss-causing germinal variants

C.-Y. Tsai, Y.-C. Lu, Y.-H. Chan, Y.-Y. Chang, S.-W. Lin, T.-C. Liu, C.-J. Hsu, P.-L. Chen, L.-W. Yang, C.-C. Wu

The paper uses molecular dynamics simulations to show how GJB2 variants cause hearing loss by altering ion channel function and demonstrates a recessive inheritance pattern in mice.

bioRxiv · May 2, 2022 · PreprintBiophysics

Actin filaments act as a size-dependent diffusion barrier around centrosomes

H. Cheng, Y.-L. Kao, L. Sharma, W.-T. Yang, S.-H. Huang, H.-R. Lin, Y.-S. Huang, C.-L. Kao, L.-W. Yang, R. Bearon, Y. C. LIN

The paper quantifies size-dependent diffusion barriers around centrosomes, showing branched actin filaments restrict molecule access based on size.

bioRxiv · Oct 21, 2021 · PreprintCell Biology

ZHX2 Promotes HIF1α Oncogenic Signaling in Triple-Negative Breast Cancer

W. Fang, C. Liao, R. Shi, J. Simon, T. Ptacek, G. Zurlo, Y. Ye, L. Han, C. Fan, C. L. Ortiz, H.-R. Lin, U. Manocha, W. Luo, W. Y. Kim, L.-W. Yang, Q. Zhang

This study identifies ZHX2 as a promoter of HIF1α oncogenic signaling in TNBC, showing its role in cell growth, invasion, and metastasis through interaction with HIF1.

bioRxiv · May 27, 2021Cancer Biology

Molecular dynamics simulations and linear response theories jointly describe biphasic responses of myoglobin relaxation and reveal evolutionarily conserved frequent communicators

B.-C. Huang, L.-W. Yang

This study uses molecular dynamics and linear response theories to explain biphasic responses in myoglobin and identifies evolutionarily conserved signal communicators.

bioRxiv · Jul 2, 2019Biophysics

An efficient timer and sizer of biomacromolecular motions

J. Chan, H.-R. Lin, K. Takemura, K.-C. Chang, Y.-Y. Chang, Y. Joti, A. Kitao, L.-W. Yang

The paper develops an efficient method to estimate the time scales and sizes of slow protein motions using elastic network models and power laws validated by NMR data.

bioRxiv · Apr 11, 2019Biophysics