Author

T. Vitale

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

P. Puigserver· 2 shared A. Asnani· 1 shared A. Kuznetsov· 1 shared A. L. Smythers· 1 shared A. Rosenzweig· 1 shared A. Vargas-Castillo· 1 shared B. M. Spiegelman· 1 shared C. Castro· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPhysiology

P. Puigserver

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cardiomyocyte PGC-1α enables physiological adaptations to endurance exercise through suppression of GDF15 and cardiac atrophy

S. A. Khetarpal, H. Li, T. Vitale, J. Rhee, L. Grauvogel, C. Castro, M. J. Mittenbühler, N. E. Houstis, A. Vargas-Castillo, A. L. Smythers, J. Liu, C. Curtin, H.-G. Sprenger, K. A. Blackmore, A. Kuznetsov, , A. Rosenzweig

This study shows that cardiomyocyte PGC-1α is essential for cardiac adaptation to endurance exercise by suppressing GDF15 and preventing cardiac atrophy in mice.

bioRxiv · Jan 30, 2024 · PreprintPhysiology

Selective Mitochondrial Respiratory Complex I Subunit Deficiency Causes Tumor Immunogenicity

J. Liang, T. Vitale, X. Zhang, T. D. Jackson, D. Yu, M. Jedrychowsk, S. P. Gygi, H. R. Widlund, K. Wucherpfennig, P. Puigserver

This study shows that deleting specific mitochondrial Complex I subunits, Ndufs4 and Ndufs6, enhances tumor immunogenicity and sensitivity to immune checkpoint blockade in mouse melanoma models.

bioRxiv · Oct 2, 2023 · PreprintCancer Biology

A CTDNEP1-lipin 1-mTOR regulatory network restricts ER membrane biogenesis to enable chromosome motions necessary for mitotic fidelity

H. Merta, J. W. Carrasquillo Rodriguez, M. I. Anjur-Dietrich, M. E. Granade, T. Vitale, T. E. Harris, D. J. Needleman, S. Bahmanyar

This study identifies a CTDNEP1-lipin 1-mTOR network that limits ER membrane biogenesis to enable proper chromosome movements and mitotic fidelity.

bioRxiv · Mar 2, 2021Cell Biology