Author

A. Kuznetsov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Rosenzweig· 2 shared A. Anand· 1 shared A. Asnani· 1 shared A. Dunkel· 1 shared A. I. Proano Vasco· 1 shared A. L. Smythers· 1 shared A. Metwaly· 1 shared A. Vargas-Castillo· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPhysiology

A. Rosenzweig

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Microbiota metabolized Bile Acids accelerate Gastroesophageal Adenocarcinoma via FXR inhibition

T. Baumeister, A. I. Proano Vasco, A. Metwaly, K. Kleigrewe, A. Kuznetsov, L. Schoemig, M. Borgmann, M. Khiat, A. Anand, K. Boettcher, D. Haller, A. Dunkel, V. Somoza, S. Reiter, C. Meng, , M. Quante

This study shows that high-fat diets promote GEAC by altering the microbiota-Bile Acid axis and inhibiting FXR, with FXR agonists like OCA slowing disease progression.

bioRxiv · Jun 11, 2024 · PreprintCancer Biology

Cardiomyocyte PGC-1α enables physiological adaptations to endurance exercise through suppression of GDF15 and cardiac atrophy

S. A. Khetarpal, H. Li, T. Vitale, J. Rhee, L. Grauvogel, C. Castro, M. J. Mittenbühler, N. E. Houstis, A. Vargas-Castillo, A. L. Smythers, J. Liu, C. Curtin, H.-G. Sprenger, K. A. Blackmore, A. Kuznetsov, , A. Rosenzweig

This study shows that cardiomyocyte PGC-1α is essential for cardiac adaptation to endurance exercise by suppressing GDF15 and preventing cardiac atrophy in mice.

bioRxiv · Jan 30, 2024 · PreprintPhysiology

Beneficial Effects of Moderate Hepatic Activin A Expression on Metabolic pathways, Inflammation, and Atherosclerosis

H. Liu, M. H. Hastings, R. Kitchen, C. Xiao, J. R. B. Guerra, A. Kuznetsov, A. Rosenzweig

This study shows that increased hepatic Activin A expression reduces atherosclerosis by lowering cholesterol, inflammation, and fat accumulation in LDLR-/- mice on a Western diet.

bioRxiv · Jul 5, 2022Pathology

ACE2 peptide fragment interacts with several sites on the SARS-CoV-2 spike protein S1

A. Kuznetsov, P. Arukuusk, H. Härk, E. Juronen, U. Langel, M. Ustav, J. Järv

The paper studies how a specific ACE2 peptide fragment affects S1-ACE2 complex formation and identifies additional binding sites on the S1 protein.

bioRxiv · Dec 29, 2020 · PreprintBiochemistry