AUTS2 controls neuronal lineage choice through a novel PRC1-independent complex and BMP inhibition
Z. Geng, Q. Wang, W. Miao, T. Wolf, J. Chavez, E. Giddings, R. Hobbs, D. J. DeGraff, Y. Wang, J. Stafford, Z. Gao
This study identifies a novel AUTS2-containing complex that inhibits BMP signaling to promote neuronal differentiation and reveals its role in neuronal lineage specification.
bioRxiv · Jun 29, 2021Biochemistry