Author

W. Miao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 2 Pathology· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:mouse· 2

Frequent Co-Authors

P. Khavari· 3 shared I. D. Ferguson· 2 shared M. Ramanathan· 2 shared Y. Wang· 2 shared A. Li· 1 shared A. Okafor· 1 shared C. Shan· 1 shared C.-C. Zhang· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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3 shared papersCancer Biology

P. Khavari

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Mitochondrial Raf1 Regulates Glutamine Catabolism

R. L. Shanderson, I. D. Ferguson, Z. Siprashvili, L. Ducoli, A. Li, W. Miao, S. Srinivasan, M. G. Velasco, Y. Li, J. Ye, P. Khavari

This paper identifies Raf1 within mitochondria where it interacts with GLS to regulate glutamine catabolism and tumorigenesis, independent of MAPK signaling.

bioRxiv · Mar 8, 2024Cancer Biology

UBE2N is essential for maintenance of skin homeostasis and suppression of inflammation

M. J. Lee, M. Ben Hammouda, W. Miao, A. Okafor, Y. Jin, H. Sun, V. Jain, V. Markovtsov, Y. Diao, S. G. Gregory, J. Y. Zhang

This study shows that UBE2N is crucial for skin homeostasis and inflammation suppression, with its loss causing inflammatory skin defects and identifying IRAK1/4 as a therapeutic target.

bioRxiv · Dec 1, 2023Pathology

Nonribosomal peptide synthetases require dynamic interaction between modular domains

C.-C. Zhang, Y.-J. Peng, X. Zeng, Y. Chen, C.-Z. Zhou, W. Miao, Y.-L. Jiang

This study investigates the dynamic interaction between the C and A domains in NRPS modules, revealing the role of the RXGR motif in adenylation activity and its prevalence across different NRPSs.

bioRxiv · Nov 13, 2023 · PreprintBiochemistry

Transcriptome analysis of protein kinase MoCK2 affect acetyl-CoA metabolism and import of CK2 interacting mitochondrial proteins into mitochondria in rice blast fungus Magnaporthe oryzae

L. Zhang, C. Shan, Y. Zhang, W. Miao, X.-L. Bing, W. Kuang, Z. Wang, R. Cui, S. Olsson

This paper investigates the role of MoCK2 in rice blast fungus metabolism and mitochondrial protein import, finding it affects acetyl-CoA production and mitochondrial function essential for pathogenesis.

Microbiology Spectrum · Dec 21, 2022Peer-reviewedMicrobiology

AUTS2 controls neuronal lineage choice through a novel PRC1-independent complex and BMP inhibition

Z. Geng, Q. Wang, W. Miao, T. Wolf, J. Chavez, E. Giddings, R. Hobbs, D. J. DeGraff, Y. Wang, J. Stafford, Z. Gao

This study identifies a novel AUTS2-containing complex that inhibits BMP signaling to promote neuronal differentiation and reveals its role in neuronal lineage specification.

bioRxiv · Jun 29, 2021Biochemistry

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

J. Meyers, M. Ramanathan, R. Shanderson, L. Donohue, I. Ferguson, M. Guo, D. Rao, W. Miao, D. Reynolds, X. Yang, Y. Zhao, Y.-Y. Yang, Y. Wang, P. Khavari

This paper identifies host proteins proximal to 17 SARS-CoV-2 viral proteins, revealing mechanisms of antiviral signaling disruption and host translation inhibition.

bioRxiv · Feb 23, 2021Microbiology

SARS-CoV-2 B.1.1.7 and B.1.351 Spike variants bind human ACE2 with increased affinity

P. Khavari, M. Ramanathan, I. D. Ferguson, W. Miao

This study measures the binding affinity of SARS-CoV-2 B.1.1.7 and B.1.351 Spike variants to human ACE2 using MST, finding increased binding for both variants compared to the original SARS-CoV-2 RBD.

bioRxiv · Feb 22, 2021Pathology

The intriguing dynamics of chromatin folding and assembly

Z. Yang, W. Miao, M. R. K. Mofrad

This study introduces a dynamic model of chromatin folding using molecular dynamics simulations and shows it can reproduce Hi-C contact matrices and reveal dynamics' impact on chromatin structure.

bioRxiv · Feb 18, 2020 · PreprintBiophysics