Author

T.-T. Pei

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:bacteria (other)· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

M.-X. Tang· 5 shared T. Dong· 5 shared H. Li· 4 shared H. Luo· 3 shared S. Yan· 3 shared X. Liang· 3 shared Z.-H. Wang· 3 shared H.-Y. Zheng· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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5 shared papersMicrobiology

M.-X. Tang

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Author profile →

5 papers

Recent·Most cited

LLPS condensates of Fha initiate the inside-out assembly of the type VI secretion system

T.-T. Pei, Y. An, X.-Y. Wang, H. Luo, Y. Kan, H. Li, M.-X. Tang, Z.-Y. Ye, J.-X. Liang, T. Jian, H.-Y. Zheng, Z.-H. Wang, X. Liang, M. Zhang, X. Liu, T. Dong

This study identifies Fha as the initiator of T6SS assembly in Acidovorax citrulli, showing it forms LLPS condensates that recruit T6SS components, revealing an inside-first assembly model.

bioRxiv · Dec 21, 2023 · PreprintMicrobiology

Systematic mutagenesis reveals critical effector functions in the assembly and dueling of the H1-T6SS in Pseudomonas aeruginosa

L.-L. Wu, T.-T. Pei, S. Yan, M.-X. Tang, L.-W. Wu, H. Li, X. Liang, S. Sun, T. Dong

This study systematically mutagenizes H1-T6SS effectors and VgrG proteins in Pseudomonas aeruginosa to reveal their roles in T6SS assembly and dueling responses.

bioRxiv · Sep 14, 2022 · PreprintMicrobiology

A dueling-competent signal-sensing module guides precise delivery of cargo proteins into target cells by engineered Pseudomonas aeruginosa

T. Dong, L.-L. Wu, S. Yan, T.-T. Pei, M.-X. Tang, H. Li, X. Liang, S. Sun

This paper introduces a protein delivery platform called DUEC that selectively delivers cargo into target cells using engineered bacterial systems.

bioRxiv · Sep 2, 2022Microbiology

Breaching the cell-envelope barriers of gram-positive and fungal microbes by a type VI secretion system in Acidovorax citrulli

T.-T. Pei, Y. Kan, Z.-H. Wang, M.-X. Tang, H. Li, S. Yan, Y. Cui, H.-Y. Zheng, H. Luo, T. Dong

This study identifies a type VI secretion system in Acidovorax citrulli that can breach gram-positive and fungal cell envelopes, with RhsB as a key effector.

bioRxiv · May 31, 2021 · PreprintMicrobiology

Abiotic factors modulate interspecies competition mediated by the type VI secretion system effectors in Vibrio cholerae

M.-X. Tang, T. Dong, T.-t. Pei, Z.-H. Wang, H. Luo, X.-Y. Wang

This study shows that abiotic factors like cations and temperature influence the effectiveness of Vibrio cholerae's type VI secretion system effectors in interspecies competition.

bioRxiv · May 27, 2021Microbiology