Author

X.-Y. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:E. coli· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2

Frequent Co-Authors

H. Luo· 2 shared M.-X. Tang· 2 shared T. Dong· 2 shared T.-T. Pei· 2 shared Z.-H. Wang· 2 shared A. W. Kahsai· 1 shared A. Zheng· 1 shared A.-L. Huang· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

H. Luo

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

LLPS condensates of Fha initiate the inside-out assembly of the type VI secretion system

T.-T. Pei, Y. An, X.-Y. Wang, H. Luo, Y. Kan, H. Li, M.-X. Tang, Z.-Y. Ye, J.-X. Liang, T. Jian, H.-Y. Zheng, Z.-H. Wang, X. Liang, M. Zhang, X. Liu, T. Dong

This study identifies Fha as the initiator of T6SS assembly in Acidovorax citrulli, showing it forms LLPS condensates that recruit T6SS components, revealing an inside-first assembly model.

bioRxiv · Dec 21, 2023 · PreprintMicrobiology

SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia

Y.-W. Luo, J.-P. Zhou, H. Ji, A. Zheng, X. Wang, Z. Dai, Z. Luo, F. Cao, X.-Y. Wang, Y. Bai, D. Chen, Y. Chen, Q. Wang, Y. Yang, X. Zhang, , K.-F. Tang

This study shows that SARS-CoV-2 N protein reduces Dicer, XPO5, SRSF3, and hnRNPA3, leading to pneumonia, and that inhibitors can reverse this effect.

bioRxiv · Oct 3, 2023 · PreprintMicrobiology

Small change, big difference: A novel praziquantel derivative P96 with multistage antischistosomal activity for chemotherapy of schistosomiasis japonica

J. Xu, L.-L. Dong, H. Sun, P. Huang, R.-Z. Zhang, X.-Y. Wang, D.-Q. Sun, C.-M. Xia

This paper introduces a novel praziquantel derivative, P96, which shows improved antischistosomal activity against all developmental stages of Schistosoma japonicum compared to praziquantel.

bioRxiv · Mar 6, 2023 · PreprintPharmacology & Toxicology

Abiotic factors modulate interspecies competition mediated by the type VI secretion system effectors in Vibrio cholerae

M.-X. Tang, T. Dong, T.-t. Pei, Z.-H. Wang, H. Luo, X.-Y. Wang

This study shows that abiotic factors like cations and temperature influence the effectiveness of Vibrio cholerae's type VI secretion system effectors in interspecies competition.

bioRxiv · May 27, 2021Microbiology

A Genetically Encoded Trimethylsilyl 1D 1H-NMR Probe for Conformation Change in Large Membrane Protein Complexes

Q. Liu, Q.-t. He, X.-x. Lyu, F. Yang, Z.-l. Zhu, P. Xiao, Z. Yang, F. Zhang, Z.-y. Yang, X.-y. Wang, P. Sun, Q.-w. Wang, C.-x. Qu, Z. Gong, J.-Y. Lin, , J. Sun

The paper introduces a genetically encoded 1D 1H-NMR probe for studying conformational changes in large membrane protein complexes, demonstrating its effectiveness with minimal protein and time.

bioRxiv · Dec 18, 2019 · PreprintBiochemistry