Author

V. Espinosa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Rivera· 4 shared K. A. M. Mills· 2 shared M. A. Aufiero· 2 shared Y. Guo· 2 shared A. D. Luster· 1 shared A. Jhingran· 1 shared A. K. Caffrey-Carr· 1 shared A. Lemenze· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

A. Rivera

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

GM-CSF-mediated epithelial-immune cell crosstalk orchestrates pulmonary immunity to Aspergillus fumigatus

K. A. M. Mills, F. Westermann, V. Espinosa, E. Rosiek, J. V. Desai, M. A. Aufiero, Y. Guo, K. A. Mitchell, S. Tuzlak, D. De Feo, M. S. Lionakis, A. Rivera, B. Becher, T. M. Hohl

This study identifies GM-CSF produced by SPC+ epithelial cells as critical for neutrophil-mediated immunity against Aspergillus fumigatus, enhancing fungal killing and host survival.

bioRxiv · Jan 3, 2024 · PreprintImmunology

Lung macrophages mediate helminth resistance through differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion

F. Chen, D. W. El-Naccache, J. J. Ponessa, A. Lemenze, V. Espinosa, W. Wu, K. Lothstein, L. Jin, O. Antao, J. S. Weinstein, P. Damani-Yokota, K. Khanna, P. J. Murray, A. Rivera, M. C. Siracusa, W. C. Gause

This study identifies lung macrophages that kill helminths by depleting arginine through differential activation of recruited monocyte-derived alveolar macrophages.

bioRxiv · Oct 2, 2020 · PreprintImmunology

MDA5 is an essential vita-PAMP sensor necessary for host resistance against Aspergillus fumigatus

X. Wang, A. K. Caffrey-Carr, K.-w. Liu, V. Espinosa, W. Croteau, S. Dhingra, A. Rivera, R. A. Cramer, J. J. Obar

This study shows MDA5 is essential for host resistance against Aspergillus fumigatus through type I and III interferon signaling and antifungal neutrophil activity.

bioRxiv · Jul 6, 2020Immunology

During Aspergillus infection, neutrophil, monocyte-derived DC, and plasmacytoid DC enhance innate immune defense through CXCR3-dependent crosstalk

Y. Guo, S. Kasahara, A. Jhingran, N. L. Tosini, B. Zhai, M. A. Aufiero, K. A. M. Mills, M. Gjonbalaj, V. Espinosa, A. Rivera, A. D. Luster, T. Hohl

The paper shows that pDCs enhance innate immune defense against Aspergillus by amplifying neutrophil activity through CXCR3-dependent crosstalk during infection.

bioRxiv · May 5, 2020Immunology