V. J. DiRita

Fitness Factor Genes Conserved within the Multi-species Core Genome of Gram-negative Enterobacterales Species Contribute to Bacteremia Pathogenesis

The paper identifies 18 conserved fitness genes in Enterobacterales species that contribute to bacteremia pathogenesis by testing mutants in a mouse model and finding attenuation in multiple organs.

Gut metabolite L-lactate supports Campylobacter jejuni population expansion during acute infection

This study identifies L-lactate as a key metabolite supporting Campylobacter jejuni growth during acute infection in ferrets, revealing a regulatory mechanism involving the LctR protein.

Activation of a Vibrio cholerae CBASS anti-phage system by quorum sensing and folate depletion

This study identifies that Vibrio cholerae's CBASS anti-phage system is activated by quorum sensing and folate depletion, revealing mechanisms for its deployment and activation.

An essential host dietary fatty acid promotes TcpH inhibition of TcpP proteolysis enabling virulence gene expression in Vibrio cholerae

Independent Promoter Recognition by TcpP Precedes Cooperative Promoter Activation by TcpP and ToxR

The paper investigates TcpP's ability to recognize the toxT promoter independently of ToxR using single-molecule tracking in live cells.

Aerobic metabolism in Vibrio cholerae is required for population expansion during infection

This study identifies oxidative metabolism of host substrates like mucin as critical for Vibrio cholerae population expansion during infection.

Phosphate transporter PstSCAB of Campylobacter jejuni is essential for lactate-dependent growth and colonization in chickens

This study shows that the phosphate transporter PstSCAB is essential for Campylobacter jejuni's growth on lactate and its ability to colonize chickens.

SMAUG: Analyzing single-molecule tracks with nonparametric Bayesian statistics

SMAUG uses nonparametric Bayesian statistics to analyze single-molecule trajectories, providing mobility states, diffusion coefficients, and transition probabilities in both prokaryotic and eukaryotic systems.