Author

V. Sahu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

H. Nakagawa· 3 shared D. Basu· 2 shared E. A. White· 2 shared I. M. Morgan· 2 shared P. A. Gimotty· 2 shared P. Rajagopalan· 2 shared A. Hickman· 1 shared A. K. Rustgi· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCancer Biology

H. Nakagawa

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3 papers

Recent·Most cited

Cancer-associated DNA Hypermethylation of Polycomb Targets Requires DNMT3A Dual Recognition of Histone H2AK119 Ubiquitination and the Nucleosome Acidic Patch

K. H. Gretarsson, S. Abini-Agbomson, S. Gloor, D. N. Weinberg, J. L. McCuiston, V. U. N. S. Kumary, A. Hickman, V. Sahu, R. Lee, X. Xu, N. Lipieta, S. Flashner, O. A. Adeleke, I. K. Popova, H. Taylor, , C. Lu

The paper identifies a critical binding interface in DNMT3A1 that facilitates DNA hypermethylation at Polycomb target genes by recognizing H2AK119Ub and the nucleosome acidic patch.

bioRxiv · Mar 18, 2024Cancer Biology

Human papilloma virus E6 regulates therapy responses in oropharyngeal cancer by repressing the PGC-1α/ERRα axis

M. K. Sannigrahi, P. Rajagopalan, L. Lai, X. Liu, V. Sahu, H. Nakagawa, J. B. Jalaly, R. M. Brody, I. M. Morgan, B. E. Windle, X. Wang, P. A. Gimotty, D. P. Kelly, E. A. White, D. Basu

This study shows that HPV E6 reduces mitochondrial antioxidant capacity and therapy resistance in oropharyngeal cancer by suppressing the PGC-1α/ERRα pathway.

bioRxiv · May 4, 2022 · PreprintCancer Biology

Identifying predictors of HPV-related head and neck squamous cell carcinoma progression and survival through patient-derived models

N. D. Facompre, P. Rajagopalan, V. Sahu, A. T. Pearson, K. T. Montone, C. D. James, F. O. Gleber-Netto, G. S. Weinstein, J. Jalaly, A. Lin, A. K. Rustgi, H. Nakagawa, J. A. Califano, C. R. Pickering, E. A. White, , D. Basu

This study identifies predictors of HPV-related head and neck squamous cell carcinoma progression and survival using patient-derived models and finds associations between mutational burden and E2F target dysregulation with clinical outcomes.

bioRxiv · Jun 17, 2019Cancer Biology