Author

W. Becker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

K. Petzold· 2 shared A. Chen· 1 shared A. J. Rogers· 1 shared A. J. Wilk· 1 shared A. L. Blomkalns· 1 shared A. V. Gayer· 1 shared B. P. Yakimov· 1 shared B. Parks· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

K. Petzold

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Elucidating microRNA-34a organisation within Human Argonaute-2 by DNP MAS NMR

R. Dasgupta, W. Becker, K. Petzold

The paper uses DNP MAS NMR to study the structural organization of miR-34a in hAgo2 and its interaction with SIRT1 mRNA, revealing conformational changes and dynamic states.

bioRxiv · Mar 28, 2024Biochemistry

Biophysics of microRNA-34a targeting and its influence on down-regulation

L. Sweetapple, D. Kosek, E. Banijamali, W. Becker, J. Mueller, C. Karadiakos, L. Baronti, I. Guzzetti, D. Schritt, A. Chen, E. R. Andersson, K. Petzold

This study investigates how miR-34a interacts with its mRNA targets and how AGO2 modulates their binding affinity and structure, revealing structural determinants of repression efficacy.

bioRxiv · Feb 14, 2024Biophysics

Label-free sensing of cells with fluorescence lifetime imaging: the quest for metabolic heterogeneity

E. A. Shirshin, M. V. Shirmanova, A. V. Gayer, M. M. Lukina, E. E. Nikonova, B. P. Yakimov, G. S. Budylin, V. V. Dudenkova, N. I. Ignatova, D. V. Komarov, V. V. Yakovlev, W. Becker, E. V. Zagaynova, V. V. Shcheslavskiy, M. O. Scully

This study demonstrates a novel FLIM data analysis approach to better detect metabolic heterogeneity in cancer cells, validated through chemotherapy-treated cell imaging.

bioRxiv · Jan 12, 2022Cancer Biology

Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in COVID-19

A. J. Wilk, M. J. Lee, B. Wei, B. Parks, R. Pi, G. J. Martinez-Colon, T. Ranganath, N. Q. Zhao, S. Taylor, W. Becker, Stanford COVID-19 Biobank, D. Jimenez-Morales, A. L. Blomkalns, R. O'Hara, E. A. Ashley, , C. A. Blish

Single-cell multi-omic profiling identifies immune dysregulation in severe COVID-19, including neutrophil hyperactivation and anti-inflammatory monocytes.

bioRxiv · Dec 18, 2020Immunology