Author

W. Bloch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 5 Organism:human· 4 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

A. Schenk· 2 shared B. Schermer· 2 shared B. Schumacher· 2 shared S. Koehler· 2 shared T. Benzing· 2 shared A. Gerken· 1 shared A. J. Metcalfe· 1 shared A. M. Mandel· 1 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

A. Schenk

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Acute exercise increases systemic kynurenine pathway metabolites and activates the AHR in human PBMCs

N. Joisten, D. Walzik, A. Schenk, A. J. Metcalfe, S. Belen, K. Schaaf, D. Jacko, S. Gehlert, P. Spiliopoulou, A.-M. Garzinsky, M. Thevis, L. Rappelt, L. Donath, S. G. Meuth, W. Bloch, P. Zimmer

This study shows acute exercise increases kynurenine pathway metabolites and activates the AHR in human PBMCs, linking exercise to immune modulation via this pathway.

bioRxiv · Jan 17, 2024 · PreprintImmunology

Transglutaminase mediated asprosin oligomerization allows its tissue storage as fibers

Y. A. Morcos, G. Pryymachuk, S. Luetke, A. Gerken, A. R. Godwin, T. A. Jowitt, N. Piekarek, T. Hoffmann, A. Niehoff, M. Odenthal, U. Drebber, O. Grisk, Y. Ladilov, W. Bloch, B. Callewaert, , G. Sengle

The paper identifies transglutaminase-mediated asprosin oligomerization and extracellular fiber formation in connective tissues, suggesting a new mechanism for tissue storage and regulation of asprosin bioavailability.

bioRxiv · Jan 4, 2022 · PreprintBiochemistry

Loss of genome maintenance accelerates podocyte damage

F. Braun, A. M. Mandel, L. Blomberg, M. N. Wong, G. Chatzinikolaou, V. Nair, R. A. Akbar-Hase, V. G. Puelles, D. H. Meyer, P. J. McCown, F. Haas, M. Rahmatollahi, D. Fermin, G. Slaats, T. Bork, , C. E. Kurschat

This study shows that loss of DNA repair gene Ercc1 in podocytes leads to DNA damage, proteinuria, and kidney disease, linked to mTORC1 activation and aging.

bioRxiv · Sep 13, 2020 · PreprintCell Biology

Influence of normobaric hypoxic exercise on endothelial progenitor cell senescence by in vitro cultivation with conditioned media

J.-F. Harmsen, D. Nebe, K. Brixius, A. Schenk, W. Bloch

This study investigates how normobaric hypoxic exercise affects endothelial progenitor cell senescence using in vitro cultivation with autologous serum.

bioRxiv · Feb 16, 2020 · PreprintPhysiology

Par3A and Par3B orchestrate podocyte architecture by regulating RhoA levels

S. Koehler, J. Odenthal, D. U. Jess, M. Hoehne, C. Juengst, F. Graewe, M. Helmstaedter, H. Hagmann, G. Walz, W. Bloch, C. Niessen, B. Schermer, A. Wodarz, B. Denholm, T. Benzing, , P. T. Brinkkoetter

This study shows that Par3A and Par3B regulate RhoA levels and podocyte architecture through interactions with Synaptopodin and CD2AP in mouse and Drosophila models.

bioRxiv · Feb 10, 2020 · PreprintCell Biology

Activation of the endoplasmic reticulum unfolded protein response reverses an inflammation-like response to cytoplasmic DNA

A. Williams, F. Heider, J.-E. Messling, W. Bloch, B. Schumacher

The paper shows that in C. elegans, persistent cytoplasmic DNA causes tissue degeneration through impaired protein homeostasis, which can be reversed by activating the UPRER or using N-acetylglucosamine.

bioRxiv · Oct 11, 2018Cell Biology