X. Chen

This study demonstrates that Nano-DOX-loaded TAM can reprogram GBM cells to an anti-GBM phenotype through DAMP emission, enhancing immune response and reducing tumor growth.

This study identifies lysine fatty acylation as a regulatory mechanism for K-Ras4a, showing that SIRT2-mediated defatty-acylation promotes oncogenic activity by enhancing endomembrane localization and interaction with A-Raf.

The paper examines how gene expression variability across cells and species influences innate immune responses, finding that rapidly diverging genes show high variability while regulatory genes are conserved.

The paper shows that some Arabidopsis accessions grow larger rosettes under zinc deficiency due to delayed flowering, which prolongs vegetative growth.

The paper presents a programmable optical stimulator for Drosophila eyes that induces retinal degeneration using blue light, showing it can reliably create environmental ocular stress.