Cell BiologybioRxiv
PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates
Y.-f. Xu, J. Sun, X. Yu…·Y.-c. Song
This study identifies how PTP-MEG2 regulates exocytosis by dephosphorylating specific sites on NSF, DYNAMIN2, and MUNC18-1, revealing distinct structural mechanisms for substrate recognition.
DOI 10.15252/embr.202052141