Author

Y.-L. Wu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cell Biology· 3 Physiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Assay:fluorescence / live-cell microscopy· 4 Research Focus:clustering· 2 Approach:deep learning· 2 Organism:human· 2 Assay:imaging· 2 Approach:statistical model· 2

Frequent Co-Authors

J. Ries· 5 shared M. Mund· 4 shared P. Hoess· 3 shared A. Tschanz· 2 shared K. Cieslinski· 2 shared S. J. Hoerner· 2 shared U. Matti· 2 shared Y. Li· 2 shared

Activity by Year

2019-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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5 shared papersBiophysics

J. Ries

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Particle fusion of Single Molecule Localization Microscopy data reveals dimer structure of Nup96 in Nuclear Pore Complex

W. Wang, A. J. Jakobi, Y.-l. Wu, J. J. Ries, S. Stallinga, B. Rieger

The paper uses particle fusion of single molecule localization microscopy data to determine the dimer structure of Nup96 in the Nuclear Pore Complex, showing 32 copies per pore.

bioRxiv · Oct 4, 2022 · PreprintCell Biology

Nanoscale structural organization and stoichiometry of the budding yeast kinetochore

K. Cieslinski, Y.-L. Wu, L. Nechyporenko, S. J. Hoerner, D. Conti, M. Skruzny, J. Ries

This study uses single-molecule localization microscopy to analyze the structure and stoichiometry of the budding yeast kinetochore, proposing a quantitative model based on nanoscale measurements.

bioRxiv · Dec 1, 2021Cell Biology

DNA-free CRISPR-Cas9 gene editing of tetraploid tomatoes using protoplast regeneration

C.-T. Hsu, Y.-H. Yuan, P.-X. Zheng, F.-H. Wu, Q.-W. Cheng, Y.-L. Wu, S. Lin, J.-J. Yue, Y.-H. Cheng, S.-I. L. Lin, M.-C. Shih, J. Sheen, Y.-C. Lin, C.-S. Lin

DNA-free CRISPR-Cas9 editing in wild tomatoes generates stable, inheritable diploid and tetraploid regenerants without chromosomal changes or off-target effects.

bioRxiv · Nov 2, 2021 · PreprintPlant Biology

Superresolution microscopy reveals partial preassembly and subsequent bending of the clathrin coat during endocytosis

M. Mund, A. Tschanz, Y.-L. Wu, F. Frey, J. L. Mehl, M. Kaksonen, O. Avinoam, U. S. Schwarz, J. Ries

The paper uses superresolution microscopy to show clathrin coats partially assemble on flat membranes before bending, and introduces a model to explain this process.

bioRxiv · Oct 12, 2021Cell Biology

Maximum-likelihood model fitting for quantitative analysis of SMLM data

Y.-L. Wu, P. Hoess, A. Tschanz, U. Matti, M. Mund, J. Ries

LocMoFit is an open-source framework that fits models to SMLM data using maximum likelihood estimation to extract biological insights from single-molecule localization coordinates.

bioRxiv · Aug 30, 2021Biophysics

Long-Term Outcomes of Pediatric Graves Disease Patients Treated with Anti-Thyroid Drugs: Experience from a Taiwan Medical Center

Y.-T. Chiang, W.-H. Ting, C.-Y. Huang, S.-K. Huang, C.-I. Chan, B.-W. Cheng, C.-H. Lin, Y.-L. Wu, C.-M. Hung, H.-J. Li, C.-J. Chan, Y.-J. Lee

This study examines long-term outcomes of pediatric Graves disease patients treated with anti-thyroid drugs, finding that younger age, no family history of thyroid disease, and lower TRAb levels are associated with remission.

bioRxiv · Apr 25, 2019 · PreprintPhysiology

Nuclear pores as versatile reference standards for quantitative superresolution microscopy

J. V. Thevathasan, M. Kahnwald, K. Cieslinski, P. Hoess, S. K. Peneti, M. Reitberger, D. Heid, K. C. Kasuba, S. J. Hoerner, Y. Li, Y.-L. Wu, M. Mund, U. Matti, P. M. Pereira, R. Henriques, , J. Ries

The paper uses genome-edited cell lines with labeled nuclear pore complexes to serve as reference standards for quantitative superresolution microscopy.

bioRxiv · Mar 20, 2019Biophysics

Depth-dependent PSF calibration and aberration correction for 3D single-molecule localization

Y. Li, Y.-L. Wu, P. Hoess, M. Mund, J. Ries

This paper develops a method to correct depth-induced aberrations in 3D single-molecule localization microscopy by using an imperfect PSF model and post-processing error correction.

bioRxiv · Feb 21, 2019Biophysics