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11 papers
Recent·Most cited
T. Deguchi, M. K. Iwanski, E.-M. Schentarra, C. Heidebrecht, L. Schmidt, J. Heck, T. Weihs, S. Schnorrenberg, P. Hoess, S. Liu, V. Chevyreva, K.-M. Noh, L. C. Kapitein, J. Ries
This study uses MINFLUX to track motor protein stepping in living cells and resolve their spatial organization on microtubules.
bioRxiv · Jul 25, 2022Biophysics
K. Gwosch, F. Balzarotti, J. K. Pape, P. Hoess, J. Ellenberg, J. Ries, U. Matti, R. Schmidt, S. J. Sahl, S. W. Hell
The paper re-analyzes MINFLUX 3D imaging data to confirm its high localization precision and discuss its implications for structural biology.
bioRxiv · May 13, 2022 · PreprintBiophysics
Y.-L. Wu, P. Hoess, A. Tschanz, U. Matti, M. Mund, J. Ries
LocMoFit is an open-source framework that fits models to SMLM data using maximum likelihood estimation to extract biological insights from single-molecule localization coordinates.
bioRxiv · Aug 30, 2021Biophysics
N. Lardon, L. Wang, A. Tschanz, P. Hoess, M. Tran, E. D'Este, J. Ries, K. Johnsson
This paper describes a method to systematically tune the spirocyclization equilibrium of rhodamines to create probes for different super-resolution microscopy techniques.
bioRxiv · May 20, 2021Cell Biology
V. Jimenez Sabinina, M. J. Hossain, J.-K. Heriche, P. Hoess, B. Nijmeijer, S. Mosalaganti, M. Kueblbeck, A. Callegari, A. Szymborska, M. Beck, J. Ries, J. Ellenberg
The paper uses 3D super-resolution microscopy and computational methods to map the 3D structure of the Nuclear Pore Complex in human cells, revealing variable conformations of its subunits.
bioRxiv · Nov 27, 2020Cell Biology
K. C. Gwosch, J. K. Pape, F. Balzarotti, P. Hoess, J. Ellenberg, J. Ries, S. W. Hell
The paper demonstrates MINFLUX nanoscopy achieves 1-3 nanometer 3D-resolution in living cells using a doughnut-shaped excitation beam and iterative localization.
bioRxiv · Aug 13, 2019Biophysics
M. S. Frei, P. Hoess, M. Lampe, B. Nijmeijer, M. Kueblbeck, J. Ellenberg, J. Ries, S. Pitsch, L. Reymond, K. Johnsson
This paper introduces a new photoactivatable fluorophore that enables live-cell super-resolution microscopy without caging groups or side-products.
bioRxiv · May 4, 2019Biophysics
J. V. Thevathasan, M. Kahnwald, K. Cieslinski, P. Hoess, S. K. Peneti, M. Reitberger, D. Heid, K. C. Kasuba, S. J. Hoerner, Y. Li, Y.-L. Wu, M. Mund, U. Matti, P. M. Pereira, R. Henriques, , J. Ries
The paper uses genome-edited cell lines with labeled nuclear pore complexes to serve as reference standards for quantitative superresolution microscopy.
bioRxiv · Mar 20, 2019Biophysics
Y. Li, Y.-L. Wu, P. Hoess, M. Mund, J. Ries
This paper develops a method to correct depth-induced aberrations in 3D single-molecule localization microscopy by using an imperfect PSF model and post-processing error correction.
bioRxiv · Feb 21, 2019Biophysics
Y. Li, M. Mund, P. Hoess, U. Matti, B. Nijmeijer, V. Jimenez Sabinina, J. Ellenberg, I. Schoen, J. Ries
The paper introduces a fast and precise 3D localization method for arbitrary PSFs, achieving high resolution and speed on standard microscopes.
bioRxiv · Aug 10, 2017Biophysics