gp130/STAT3 signaling is required for homeostatic proliferation and anabolism in postnatal growth plate and articular chondrocytes
N. Liu, Y. Lin, L. Li, J. Lu, D. Geng, J. Zhang, T. Jashashvili, Z. Buser, J. Magallanes, J. Tassey, R. Shkhyan, A. Sarkar, N. Lopez, L. Wang, F. Petrigliano, , D. Evseenko
This study shows that gp130/STAT3 signaling is essential for chondrocyte proliferation and anabolism, with loss leading to growth defects and cartilage dysfunction.
bioRxiv · Oct 12, 2021Cell Biology