Inactivation of a non-canonical gp130 signaling arm attenuates chronic systemic inflammation and multimorbidity induced by a high-fat diet.
Y. Lee, A. Sarkar, J. Tassey, J. N. Levi, S. Lee, N. Q. Liu, A. C. Drake, J. Magallanes, J. Lu, D. Ge, H. Tang, T. Mkaratigwa, F. Bian, R. Shkhyan, M. A. Bonaguidi, D. Evseenko
This study shows that inhibiting a non-canonical gp130 signaling pathway reduces chronic inflammation and multimorbidity in a high-fat diet model.
bioRxiv · Apr 8, 2024 · PreprintCell Biology