Author

Z.-Z. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

J. Z. Long· 2 shared R. E. Gerszten· 2 shared S. Deng· 2 shared U. Tahir· 2 shared V. L. Li· 2 shared W. Wei· 2 shared X. Lyu· 2 shared X. Shi· 2 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersPhysiology

J. Z. Long

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Author profile →

2 papers

Recent·Most cited

Lac-Phe mediates the anti-obesity effect of metformin

S. Xiao, V. L. Li, X. Lyu, X. Chen, W. Wei, F. Abbasi, J. Knowles, S. Deng, G. Tiwari, X. Shi, S. Deng, L. Farrell, Z.-Z. Chen, K. Taylor, X. Guo, , J. Z. Long

This study identifies Lac-Phe as a mediator of metformin's anti-obesity effects through experiments in mice and human cohorts.

bioRxiv · Nov 2, 2023 · PreprintPhysiology

CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels

J. T. Tanzo, V. L. Li, A. L. Wiggenhorn, M. D. M. Garzon, W. Wei, X. Lyu, W. Dong, U. Tahir, Z.-Z. Chen, D. E. Cruz, S. Deng, X. Shi, S. Zheng, Y. Guo, M. Sims, , M. D. Benson

The paper identifies CYP4F2 as a human-specific genetic determinant of plasma N-acyl amino acid levels and shows its role in metabolic diversification.

bioRxiv · Mar 9, 2023Biochemistry