yeast

The paper investigates the distinct roles of Atg3 and Atg10 in autophagosome formation in yeast, showing Atg3 affects lipidation and size while Atg10 controls number.

This study shows indaziflam, a cellulose biosynthesis inhibitor herbicide, only affects organisms with cellulose-containing cell walls, not those with chitin or glycoprotein walls.

This study shows that cortical ER-PM contact sites maintain nuclear envelope integrity and proper mitotic nuclear segregation by preventing membrane damage and supporting nuclear dynamics.

The paper uses deep mutational scanning to analyze resistance mutations in Fks1, revealing distinct resistance landscapes for echinocandins and triterpenoids, including a novel triterpenoid-specific hotspot.

This paper uses Hi-C data to infer 3D genome structure and chromatin dynamics in budding yeast without prior assumptions about nuclear organization.

The paper predicts a cohesin acetylation complex in budding yeast that interacts with nicked DNA and confirms its function through experiments.

This study shows that yeast Gcn2 promotes P-body formation through eIF2α phosphorylation and Smu2-dependent mRNA granule maturation, even when eIF2α phosphorylation is blocked.

This study shows that Mto1 and Mto2 stabilize γ-tubulin positions in fission yeast γ-TuRCs, enabling microtubule nucleation through structural modulation.

This study reveals how mitochondrial complex III assembles from preformed matrix domain modules, showing dynamic subunit exchange and the role of specific residues in assembly and disease.

The paper shows that FACT facilitates Ubp10 release from nucleosomes after H2B deubiquitination, revealing release as the rate-limiting step for Ubp10 turnover.

This study identifies three distinct pathways maintaining kinetochore integrity during meiosis in budding yeast, with distinct temporal requirements and interactions involving Ctf19cCCAN, Mif2CENP-C, and Cse4CENP-A-Okp1CENP-Q-Ame1CENP-U.

This study identifies extensive horizontal gene transfer in the fungus gnat Bradysia coprophila, showing these genes contribute to stress tolerance and ecological adaptation.

The paper uses R-DeeP to show stress-induced compartment-specific RNA buffering of protein aggregation in yeast, with nuclear RNA retention protecting nuclear proteins from aggregation.

The paper identifies widespread Saccharomyces hybridization in agave fermentations, showing multiple independent origins and asymmetric parental genetic diversity.

The paper develops a pipeline to collect, characterize, and scale wild yeast for beer brewing, identifying interventions to overcome industrial fermentation challenges.

This study shows that evolution can restore cellular function without conserving microscopic organization, leading to novel molecular phenotypes in budding yeast.