Author

A. Favier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Cell Biology· 1 Ecology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:chromatin & epigenetic regulation· 2 Approach:deep learning· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

B. Brutscher· 2 shared J. Boisbouvier· 2 shared P. Gans· 2 shared P. Macek· 2 shared A. Andrieux· 1 shared A. C. Sivertsen· 1 shared a. Israel· 1 shared A. Sanchez· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBiochemistry

B. Brutscher

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Author profile →

6 papers

Recent·Most cited

Predictive microbial community changes across a temperature gradient

X. Sun, J. Folmar, A. Favier, N. Pyenson, A. Sanchez, M. Rebolleda-Gomez

This study predicts microbial community changes across a temperature gradient by analyzing metabolic responses in synthetic environments.

bioRxiv · Jul 28, 2023 · PreprintEcology

Structural analysis shows that the BIR2 domain of E3 ligase XIAP binds across the RIP2 kinase dimer interface

M. Lethier, M. Hons, A. Favier, B. Brutscher, E. Boeri Erba, S. Cusack, E. Pellegrini

The paper determines the structure of the RIP2K-XIAP BIR2 complex, revealing its dimeric conformation and molecular mechanisms of interaction.

bioRxiv · Oct 14, 2022Biochemistry

Visualizing the Transiently Populated Closed-State of Human HSP90 ATP Binding Domain

F. Henot, E. Rioual, A. Favier, P. Macek, E. Crublet, P. Josso, B. Brutscher, M. Frech, P. Gans, C. Loison, J. Boisbouvier

The paper identifies a metastable excited state in the HSP90 ATP binding domain using solution NMR and mutagenesis, showing it transiently samples a closed state distant from the ground state.

bioRxiv · Mar 16, 2022 · PreprintBiophysics

Modeling disease-correlated TUBA1A mutation in budding yeast reveals a molecular basis for tubulin dysfunction

E. Denarier, K. H. Ecklund, G. Berthier, A. Favier, S. Gory, L. De Macedo, C. Delphin, A. Andrieux, S. M. Markus, C. Boscheron

This study models a TUBA1A mutation in budding yeast to reveal how it disrupts microtubule function and dynein regulation, leading to spindle positioning defects.

bioRxiv · Apr 13, 2020 · PreprintCell Biology

Nucleo-plastidic PAP8/pTAC6 couples chloroplast formation with photomorphogenesis

M. Liebers, F.-X. Gillet, a. Israel, K. Pounot, L. Chambon, M. Chieb, F. Chevalier, R. Ruedas, A. Favier, P. Gans, E. Boeri-Erba, D. Cobessi, T. Pfannschmidt, R. Blanvillain

This study identifies PAP8 as a key regulator linking chloroplast formation with photomorphogenesis by coordinating nuclear and plastid gene expression.

bioRxiv · Mar 10, 2020Plant Biology

Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex

D. Gauto, L. Estrozi, C. Schwieters, G. Effantin, P. Macek, r. sounier, A. C. Sivertsen, E. Schmidt, R. Kerfah, G. Mas, J.-P. Colletier, P. Guntert, A. Favier, G. Schoehn, J. Boisbouvier, P. Schanda

The paper integrates NMR and cryo-EM to determine the atomic structure of a large enzyme complex, achieving high precision and accuracy beyond the limitations of each method individually.

bioRxiv · Dec 16, 2018Biophysics