Author

A. Holder

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell-cell communication· 2 Organism:chicken / avian· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

D. Werling· 4 shared H. Harris· 2 shared J. Kolakowski· 2 shared A. Gibson· 1 shared A. J. Gibson· 1 shared A. Urkitza· 1 shared C. J. Rosentreter· 1 shared C. Weber· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersImmunology

D. Werling

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Inflammation-Induced Claudin-2 Upregulation Limits Pancreatitis Progression by Enhancing Tight Junction-Controlled Pancreatic Ductal Transport

S. Kesaraju, Y. Li, J. Xing, M. Tracy, K. Wannemo, A. Holder, P. Zhao, M. A. Khan, J. Kainov, N. Rana, M. Sidahmed, S. Hyoju, L. Smith, J. Matthews, S. Tay, , C. Weber

This study shows CLDN2 upregulation during pancreatitis limits disease progression by enhancing tight junction-controlled fluid transport in pancreatic ductal epithelium.

bioRxiv · Sep 1, 2023 · PreprintPathology

Characterisation of the bovine C-type lectin receptor Mincle and potential evidence for an endogenous ligand

A. Holder, J. F. Kolakowski, C. J. Rosentreter, E. Knuepfer, S. Jegouzo, O. Rosenwasser, H. Harris, L. H. Baumgaertel, A. J. Gibson, D. Werling

This study characterizes bovine Mincle, showing structural and functional similarity to human Mincle, with potential endogenous ligand recognition.

bioRxiv · Mar 20, 2023 · PreprintImmunology

Single Nucleotide Polymorphisms in the Bovine TLR2 Extracellular Domain Contribute to Breed and Species-Specific Innate Immune Functionality

M.-C. BArtens, A. Gibson, G. J. Etherington, F. di Palma, A. Holder, D. Werling, S. Willcocks

This study identifies a SNP in bovine TLR2 that contributes to breed-specific differences in innate immune response to mycobacterial antigens.

bioRxiv · Aug 23, 2021Immunology

Development of a yeast-based vaccine for Theileria parva infection in cattle

S. Goh, J. Kolakowski, A. Holder, M. Pfuhl, D. Ngugi, K. Ballingall, K. Tombacz, D. Werling

This paper develops a yeast-based vaccine for Theileria parva infection using recombinant antigens expressed on Saccharomyces cerevisiae, showing immune responses in mice and potential for oral application.

bioRxiv · Jan 30, 2021Immunology

Bovine neutrophils release extracellular traps and cooperate with macrophages in Mycobacterium avium subsp. paratuberculosis clearance in vitro

I. Ladero-Aunon, E. Molina, A. Holder, J. Kolakowski, H. Harris, A. Urkitza, J. Anguita, D. Werling, N. Elguezabal

This study investigates how bovine neutrophils and macrophages interact to clear Mycobacterium avium subsp. paratuberculosis in vitro, showing synergistic effects and reduced inflammation.

bioRxiv · Dec 30, 2020Immunology