Cell BiologybioRxiv
Hsp70/Hsp90 organizing protein (HOP) maintains CRAF kinase activity and regulates MAPK signaling by enhancing Hsp90-CRAF association
DOI 10.1080/10985549.2026.2647809
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3 papers
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A. K. Mandal, B. Ghosh, S. Karmakar, M. Prasad
This study identifies Praja1 as a ubiquitin ligase that degrades polyglutamine proteins and reduces their toxicity in neurodegenerative diseases.