Author

A. Kadioglu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 7

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 7 Organism:mouse· 5 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

M. Baltazar· 4 shared E. Waters· 2 shared J. Clarke· 2 shared M. Kjos· 2 shared M. Yang· 2 shared N. French· 2 shared S. Panagiotou· 2 shared T. Audshasai· 2 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersMicrobiology

M. Baltazar

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

The Streptococcus agalactiae LytSR two-component regulatory system promotes vaginal colonisation and virulence in vivo

H. AlQadeeb, M. Baltazar, A. Cazares, T. Poonpanichakul, M. Kjos, N. French, A. Kadioglu, M. O'Brien

This study shows that the LytSR two-component system in Streptococcus agalactiae enhances vaginal colonization and virulence by promoting biofilm formation and inflammatory responses.

Microbiology Spectrum · Nov 5, 2024Peer-reviewedMicrobiology

Hypervirulent pneumococci display high levels of nasopharyngeal shedding and rapid onward transmission

M. Baltazar, T. Audshasai, L. C. Jacques, M. Yang, A. Kadioglu

This study compares the transmission dynamics of hypervirulent serotype 1 ST217 and serotype 2 D39 pneumococci in mice, showing ST217 has higher shedding and faster transmission, especially during co-infection with influenza.

bioRxiv · Jun 17, 2023Microbiology

Pseudomonas aeruginosa utilises host-derived polyamines to facilitate antimicrobial tolerance

C. M. Hasan, A. Green, A. A. Cox, J. White, T. Jones, C. Winstanley, A. Kadioglu, M. Wright, D. R. Neill, J. L. Fothergill

This study shows that Pseudomonas aeruginosa uses host-derived polyamines, like spermidine, to enhance antimicrobial tolerance during infection, despite reduced susceptibility in vitro.

bioRxiv · Dec 15, 2021 · PreprintMicrobiology

Streptococcus pneumoniae rapidly translocates from the nasopharynx through the cribriform plate to invade and inflame the dura

T. Audshasai, J. A. Coles, S. Panagiotou, S. Khandaker, H. E. Scales, M. Kjos, M. Baltazar, J. Vignau, J. M. Brewer, A. Kadioglu, M. Yang

This study shows Streptococcus pneumoniae rapidly translocates from the nose through the cribriform plate to the meninges without entering the bloodstream.

bioRxiv · Sep 28, 2021 · PreprintMicrobiology

Long term nasopharyngeal colonization by Staphylococcus aureus determinants of adaptation

B. A. B. Salgado, E. Waters, J. C. Moran, A. Kadioglu, M. J. Horsburgh

This study identifies genetic factors in Staphylococcus aureus that promote long-term nasal colonization using a novel murine model and experimental evolution.

bioRxiv · Sep 19, 2021Microbiology

Impaired alanine transport or exposure to D-cycloserine increases the susceptibility of MRSA to beta-lactam antibiotics

L. Gallagher, R. K. Shears, C. Fingleton, L. Alvarez, E. Waters, J. Clarke, L. Bricio-Moreno, C. Campbell, A. Yadav, F. Razvi, E. O'Neill, A. O'Neill, F. Cava, P. Fey, A. Kadioglu, J. P. O'Gara

The paper shows that impairing alanine transport or exposing MRSA to D-cycloserine increases susceptibility to beta-lactam antibiotics by reducing peptidoglycan crosslinking.

bioRxiv · Sep 19, 2019Microbiology

Streptolysin production and activity is central to in vivo pathotype and disease outcome in GAS infections

J. Clarke, M. Baltazar, M. Alsahag, S. Panagiotou, M. Pouget, W. A. Paxton, G. Pollakis, D. Everett, N. French, A. Kadioglu

This study shows that streptolysin O (SLO) production and activity determine the pathotype and disease outcome in Group A Streptococcus (GAS) infections, with implications for therapeutic strategies.

bioRxiv · Jun 28, 2019 · PreprintMicrobiology