Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
C. Mrabti, N. Yang, G. Desdin-Mico, A. Alonso-Calleja, A. Vilchez-Acosta, S. Pico, A. Parras, Y. Piao, L. Schoenfeldt, S. Luo, A. Haghani, R. Brooke, M. d. C. Maza, C. Branchina, C. Yacoub Maroun, , A. Ocampo
This study shows that loss of H3K9me3 in adult mice leads to premature aging, characterized by reduced lifespan, frailty, and accelerated epigenetic aging.
bioRxiv · Jul 24, 2024 · PreprintPhysiology
J. Collins, J. M. Barra, K. Holcomb, A. Ocampo, A. Fremin, J. Akolade, A. Kratz, J. K. Hays, A. Shilleh, D. J. Hodson, J. J. Broichhagen, H. A. Russ, N. L. Farnsworth
This paper develops peptide-coated nanocapsules for targeted drug delivery to pancreatic β-cells, showing effective in vitro and in vivo targeting and cargo delivery.
bioRxiv · Jul 15, 2024Bioengineering
G. B. Phelps, J. Morin, C. Pinto, L. Schoenfeldt, S. Guilmot, A. Ocampo, K. Perez
This study evaluates 16 lifespan-extending molecules in C. elegans, confirming some effects, identifying synergies, and finding conserved effects in Drosophila.
bioRxiv · Jun 24, 2024 · PreprintPharmacology & Toxicology
N. H. Kamaludeen Mariyath, Y. Mauge, S. El Mouridi, S. Pico, A. Vilchez Acosta, J. A. de Sousa, M. Pierron, V. Praz, F. von Meyenn, C. Frokjaer-Jensen, A. Ocampo
This study induces in vivo reprogramming in C. elegans and finds it leads to heterogeneous effects on lifespan depending on developmental stage.
bioRxiv · May 3, 2024 · PreprintCell Biology
L. Gomez-Cid, A. Campo-Fonseca, M. Cervera-Negueruela, A. Ocampo, A. G Pinto, J. M. Gil-Jaurena, S. Suarez-Sancho, F. Fernandez-Aviles, J. Bermejo, L. Grigorian-Shamagian
The paper identifies an in vitro assay to predict the ageing-reversal potency of stem cell-derived extracellular vesicles in a rat model of premature cardiac senescence.
bioRxiv · Jan 28, 2024 · PreprintCell Biology
P. T. Paine, C. Rechsteiner, F. Morandini, G. Desdin Mico, C. Mrabti, A. Parras, A. Haghani, R. Brooke, S. Horvath, A. Seluanov, V. Gorbunova, A. Ocampo
The paper uses partial cellular reprogramming to reduce DNA damage in an ERCC1 mouse model of premature aging, showing restoration of the epigenetic clock and DNA repair processes.
bioRxiv · May 12, 2023Cell Biology
L. Schoenfeldt, P. T. Paine, N. H. Kamaludeen M., G. B. Phelps, C. Mrabti, K. Perez, A. Ocampo
This study shows that chemical reprogramming can improve aging-related cellular features and extend lifespan in C. elegans.
bioRxiv · Aug 29, 2022Cell Biology
J. Bacque, E. Delgado, S. Benito, M. Moreno-Lorenzo, V. Montero, H. Gil, M. Sanchez, M. C. Nieto-Toboso, J. Munoz, M. Z. Zubero-Sulibarria, E. Ugalde, E. Garcia-Bodas, J. E. Canada, J. del Romero, C. Rodriguez, , M. M. Thomson
The paper identifies CRF66_BF, a new HIV-1 circulating recombinant form of South American origin, distinct from CRF12_BF and prevalent in Paraguay.
bioRxiv · Sep 14, 2021Microbiology