Author

S. C. Lakhotia

Primary ORCID profile (0000-0003-1842-8411 · 8 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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S. C. LakhotiaiD8 papers · Banaras Hindu University

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:Drosophila· 4 Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell signaling & trafficking· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

G. Singh· 3 shared A. Bajpai· 1 shared A. Biswas· 1 shared A. G. Goodman· 1 shared A. Goel· 1 shared B. Ateeq· 1 shared D. Sinha· 1 shared M. Ray· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCell Biology

G. Singh

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Author profile →

4 papers

Recent·Most cited

Cell BiologybioRxivFeb 2, 2023

Non-canonically regulated heterochronic expression of Hsp70 drives clonal expansion and invasion in Drosophila epithelial tumors

A. Biswas, G. Singh, V. Arya…·D. Sinha

This study shows that non-canonical Hsp70 regulation via ROS-JNK-FOXO pathway drives clonal expansion and invasion in Drosophila epithelial tumors.

DOI 10.1242/jcs.264402

Drosophilaexperimental assay

𝕏 PostBluesky

Cancer BiologyCell Stress and ChaperonesPeer-reviewedJul 1, 2022

Elevation of major constitutive heat shock proteins is heat shock factor independent and essential for establishment and growth of Lgl loss and Yorkie gain mediated tumors in Drosophila

G. Singh, S. Chakraborty, S. C. Lakhotia

This study shows that constitutive heat shock proteins, not stress-inducible Hsp70, are essential for tumor growth in Drosophila, independent of HSF regulation.

DOI 10.1007/s12192-022-01283-z

Drosophilaproteomics

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Cancer BiologybioRxivPreprintApr 26, 2021

Nuclear biocondensate-forming lncRNA and cellular stress surveillance shape host cancer susceptibility

A. Bajpai, Q. T. Ahmad, S. Kundu…·P. Sinha

This study identifies hsr{omega} and its human homologs as key regulators of cancer susceptibility through stress response pathways in Drosophila and humans.

DOI 10.1101/2021.04.26.441543

Drosophilahuman

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Cell BiologybioRxivApr 13, 2019

Altered levels of hsromega lncRNAs further enhance Ras signaling during ectopically activated Ras induced R7 differentiation in Drosophila

M. Ray, G. Singh, S. C. Lakhotia

The paper shows that altering hsr{omega} lncRNA levels enhances Ras signaling in Drosophila eye discs, leading to increased R7 photoreceptors and pupal lethality.

DOI 10.1016/j.gep.2019.05.002

Drosophilabulk RNA-seq

𝕏 PostBluesky