Author

B. Fitzgerald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

C. Cui· 2 shared G. G. Foster· 2 shared I. Monroy· 2 shared I. William· 2 shared K. A. Connolly· 2 shared M. Damo· 2 shared N. S. Joshi· 2 shared A. Arrones· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersImmunology

C. Cui

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Single cell view of tumor microenvironment gradients in pleural mesothelioma

B. Giotti, K. Dolasia, w. Zhao, P. Cai, R. Sweeney, E. Merritt, E. Kiner, G. Kim, A. Bhagwat, S. Hegde, B. Fitzgerald, S. Shroff, T. Dawson, M. Garcia-Barros, J. Abdul-Ghafar, , A. Tsankov

This paper uses single-cell RNA-sequencing to analyze the tumor microenvironment in pleural mesothelioma, identifying gene programs, fetal-like endothelial cells, and a new therapeutic target.

bioRxiv · Mar 14, 2024Cancer Biology

Convergent evolution of plant prickles is drivenby repeated gene co-option over deep time

J. W. Satterlee, D. Alonso, P. Gramazio, K. M. Jenike, J. He, A. Arrones, G. Villanueva, M. Plazas, S. Ramakrishnan, M. Benoit, I. Gentile, A. Hendelman, H. Shohat, B. Fitzgerald, G. M. Robitaille, , Z. B. Lippman

The paper investigates convergent evolution of plant prickles, finding that mutations in a cytokinin gene repeatedly cause prickle loss across species.

bioRxiv · Feb 21, 2024 · PreprintEvolutionary Biology

A gut commensal protist protects against virus-mediated loss of oral tolerance

M. Siller, Y. Zeng, L. M. Sanchez, P. H. Brigleb, K. A. Sangani, M. Rana, L. Van Der Kraak, S. P. Pandey, M. J. Bender, B. Fitzgerald, L. Hedden, K. Fiske, G. M. Taylor, S. A. Rahman, H. J. Galipeau, , R. Hinterleitner

This study identifies the protist Tritrichomonas arnold as a protector against virus-induced loss of oral tolerance to gluten, showing it reduces inflammation in dendritic cells and is underrepresented in celiac disease patients.

bioRxiv · Jun 21, 2022Immunology

A reservoir of stem-like CD8 T cells in the tumor-draining lymph node maintains the ongoing anti-tumor immune response

K. A. Connolly, M. Kuchroo, A. Venkat, A. Khatun, J. Wang, I. William, N. Hornick, B. Fitzgerald, M. Damo, M. Y. Kasmani, C. Cui, E. Fagerberg, I. Monroy, A. Hutchins, J. F. Cheung, , N. S. Joshi

The paper identifies a reservoir of stem-like CD8 T cells in tumor-draining lymph nodes that sustain anti-tumor immunity by maintaining TCF1 expression and resisting terminal differentiation.

bioRxiv · Jan 27, 2021Immunology

NINJA: an inducible genetic model for creating neoantigens in vivo

M. Damo, B. Fitzgerald, Y. Lu, M. Nader, I. William, J. Cheung, K. A. Connolly, G. G. Foster, E. Akama-Garren, D.-Y. Lee, G. P. Chang, V. Gocheva, L. M. Schmidt, A. Boileve, J. H. Wilson, , N. S. Joshi

The paper develops a genetic model called NINJA to create inducible neoantigens in mice, enabling controlled T cell responses without central tolerance.

bioRxiv · Jan 9, 2020 · PreprintImmunology