Author

B. Schumann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:metagenomics· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

L. Di Vagno· 2 shared S. A. Malaker· 2 shared A. Borg· 1 shared A. Cioce· 1 shared A. G. Wrobel· 1 shared A. J. Hryckowian· 1 shared A. M. Gonzalez-Ramirez· 1 shared A. Marchesi· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

L. Di Vagno

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Xylosyltransferase Bump-and-hole Engineering to Chemically Manipulate Proteoglycans in Mammalian Cells

Z. Li, L. Di Vagno, H. Chawla, A. Ni Cheallaigh, M. Critcher, D. Sammon, D. C. Briggs, N. Chung, V. Chang, K. E. Mahoney, A. Cioce, L. D. Murphy, Y.-H. Chen, Y. Narimatsu, R. L. Miller, , B. Schumann

This paper develops a chemical genetic strategy to manipulate proteoglycan glycan attachment sites in mammalian cells using modified xylosyltransferases.

bioRxiv · Dec 20, 2023 · PreprintBiochemistry

O-Linked Sialoglycans Modulate the Proteolysis of SARS-CoV-2 Spike and Likely Contribute to the Mutational Trajectory in Variants of Concern

E. Gonzalez-Rodriguez, M. Zol-Hanlon, G. Bineva-Todd, A. Marchesi, M. Skehel, K. Mahoney, C. Roustan, A. Borg, L. Di Vagno, S. Kjaer, A. G. Wrobel, D. J. Benton, P. Nawrath, S. L. Flitsch, D. Joshi, , B. Schumann

This paper shows that O-linked sialoglycans affect SARS-CoV-2 spike proteolysis by furin and TMPRSS2, and may drive mutations in variants of concern.

bioRxiv · Sep 15, 2022Cell Biology

Butyrate differentiates permissiveness to Clostridioides difficile infection and influences growth of diverse C. difficile isolates

D. Pensinger, A. T. Fisher, H. A. Dobrila, W. Van Treuren, J. O. Gardner, S. K. Higginbottom, M. M. Carter, B. Schumann, C. Bertozzi, V. Anikst, C. Martin, E. Robilotti, J. Chow, R. H. Buck, L. S. Tompkins, , A. J. Hryckowian

This study shows butyrate reduces C. difficile fitness in mice and humans, and inhibits growth of diverse C. difficile isolates, suggesting dietary interventions could help prevent CDI.

bioRxiv · May 20, 2022Microbiology