Author

B. Singer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Ecology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:ecology & biodiversity· 1 Organism:human· 1 Research Focus:protein design· 1

Frequent Co-Authors

A. Gonzalez· 1 shared A. J. Borst· 1 shared A. Sheikh· 1 shared B. Huang· 1 shared B. I. M. Wicky· 1 shared B. Setu· 1 shared C. C. Liu· 1 shared C. Criswell· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperEcology

A. Gonzalez

Author profile →

3 papers

Recent·Most cited

Host-derived CEACAM-laden vesicles engage enterotoxigenic E. coli for elimination and toxin neutralization.

A. Sheikh, D. Ganguli, T. J. Vickers, B. Singer, J. Foulke-Abel, M. Akhtar, N. Khatoon, B. Setu, S. Basu, N. Maier, W. Beatty, S. Chakraborty, T. R. Bhuiyan, F. Qadri, M. Donowitz, J. M. Fleckenstein

The paper shows that host-derived CEACAM-laden vesicles capture ETEC and its toxins, reducing pathogen load and neutralizing toxins during infection.

bioRxiv · Jul 24, 2024 · PreprintMicrobiology

Atomically accurate de novo design of antibodies with RFdiffusion

N. R. Bennett, J. L. Watson, R. J. Ragotte, A. J. Borst, D. L. See, C. Weidle, R. Biswas, Y. Yu, E. L. Shrock, R. Ault, P. J. Y. Leung, B. Huang, I. Goreshnik, J. Tam, K. D. Carr, , D. Baker

This paper designs antibodies de novo with atomic precision using RFdiffusion and yeast display, validated by cryo-EM and biophysical methods.

bioRxiv · Mar 14, 2024Bioengineering

Metapopulations, the inflationary effect, and consequences for public health

N. Kortessis, G. Glass, A. Gonzalez, N. W. Ruktanonchai, M. W. Simon, B. Singer, R. D. Holt

The paper examines the inflationary effect in metapopulations, showing how spatiotemporal heterogeneity enhances population stability and abundance, with implications for disease spread and public health.

bioRxiv · Oct 30, 2023Ecology