Author

C. L. Moyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:drug response / drug discovery· 2 Assay:metagenomics· 2 Organism:virus· 2 Research Focus:cell type annotation· 1 Research Focus:ecology & biodiversity· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Z. Wec· 3 shared K. Chandran· 3 shared L. M. Walker· 3 shared Z. A. Bornholdt· 3 shared A. S. Wirchnianski· 2 shared D. M. Abelson· 2 shared E. Goodwin· 2 shared H. Fullerton· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersMicrobiology

A. Z. Wec

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Microbial metabolic potential of hydrothermal vent chimneys along the Submarine Ring of Fire

L. L. Murray, H. Fullerton, C. L. Moyer

This study analyzes microbial metabolic potential in hydrothermal vent chimneys using metagenomic data from five Pacific Ocean sites, identifying core taxa and genes associated with different metabolic functions.

bioRxiv · Sep 12, 2023 · PreprintMicrobiology

Seafloor Incubation Experiments at Deep-Sea Hydrothermal Vents Reveal Distinct Biogeographic Signatures of Autotrophic Communities

H. Fullerton, L. Smith, A. Enriquez, D. A. Butterfield, C. G. Wheat, C. L. Moyer

The paper investigates microbial communities in hydrothermal vent discharge, finding geographic influences on community structure despite similar environmental conditions.

bioRxiv · Jul 20, 2023Microbiology

Reversion of Ebolavirus Disease from a Single Intramuscular Injection of a pan-Ebolavirus Immunotherapeutic

E. Kuang, R. W. Cross, M. McCavitt-Malvido, D. M. Abelson, V. Borisevich, K. N. Agans, N. Mlakar, A. Marimuthu, D. J. Deer, W. S. Shestowsky, D. Kim, J. B. Geisbert, L. Zeitlin, C. L. Moyer, C. J. Roy, , Z. A. Bornholdt

This study shows that a single intramuscular dose of MBP431, a modified ebolavirus therapeutic, can reverse disease and provide protection in non-human primates.

bioRxiv · Jan 6, 2022Microbiology

Genotype-specific Features Reduce the Susceptibility of South American Yellow Fever Virus Strains to Vaccine-Induced Antibodies

D. Haslwanter, G. Lasso, A. Z. Wec, N. D. Furtado, L. M. S. Raphael, Y. Sun, S. Stransky, N. Pedreno-Lopez, A. Tse, C. A. Correia, Z. A. Bornholdt, M. Sakharkar, V. I. Avelino-Silva, C. L. Moyer, D. I. Watkins, , K. Chandran

This study shows that South American yellow fever virus strains are less susceptible to vaccine-induced antibodies due to genetic changes in the glycoprotein E.

bioRxiv · Aug 22, 2021Microbiology

Human antibody cocktail deploys multiple functions to confer pan-ebolavirus protection

A. Z. Wec, Z. A. Bornholdt, S. He, A. S. Herbert, E. Goodwin, A. S. Wirchnianski, B. M. Gunn, Z. Zhang, W. Zhu, G. Liu, D. M. Abelson, C. L. Moyer, R. K. Jangra, R. M. James, R. R. Bakken, , K. Chandran

This paper develops a human antibody cocktail, MBP134, that provides broad protection against multiple ebolaviruses, showing enhanced efficacy in guinea pigs compared to individual antibodies.

bioRxiv · Aug 20, 2018Microbiology

Structural Basis of Broad Ebolavirus Neutralization by a Human Survivor Antibody

B. R. West, A. Z. Wec, C. L. Moyer, M. L. Fusco, P. A. Illinykh, K. Huang, R. James, A. Herbert, S. Hui, A. S. Wirchnianski, E. Goodwin, M. J. Aman, L. M. Walker, J. M. Dye, A. Bukreyev, , E. O. Saphire

The paper determines the structure of a broadly neutralizing antibody against ebolavirus, identifies a conserved epitope, and explains factors affecting its activity against related viruses.

bioRxiv · Aug 19, 2018Immunology