Author

C. Rafie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1

Frequent Co-Authors

E. M. Jaffee· 2 shared L. T. Kagohara· 2 shared A. Bianchi· 1 shared A. Colaprico· 1 shared A. G. Baugh· 1 shared A. Gupta· 1 shared A. MacLean· 1 shared A. Pillai· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

E. M. Jaffee

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Author profile →

3 papers

Recent·Most cited

Mimicking the breast metastatic microenvironment: characterization of a novel syngeneic model of HER2+ breast cancer

A. G. Baugh, E. Gonzalez, V. H. Narumi, J. Kreger, Y. Liu, C. Rafie, S. Castanon, J. Jang, L. T. Kagohara, D. P. Anastasiadou, J. Leatherman, T. D. Armstrong, I. Chan, G. S. Karagiannis, E. M. Jaffee, , E. T. Roussos Torres

The paper characterizes a novel syngeneic murine breast cancer model (NT2.5-LM) that exhibits rapid and widespread metastases, enabling study of metastatic progression and therapeutic responses.

bioRxiv · Jan 25, 2024Cancer Biology

Distinct Mechanisms of Innate and Adaptive Immune Regulation Underlie Poor Oncologic Outcomes Associated with KRAS-TP53 Co-Alteration in Pancreatic Cancer

J. Datta, A. Bianchi, I. De Castro Silva, N. U. Deshpande, L. L. Cao, S. Mehra, S. Singh, C. Rafie, X. Sun, X. Chen, X. Dai, A. Colaprico, P. Sharma, A. R. Dosch, A. Pillai, , N. B. Merchant

bioRxiv · May 1, 2022Cancer Biology

Phenotypic shifts of tumor associated macrophages and STAT3 mediated suppression of myeloid derived suppressor cells drive sensitization of HER2+ tumor immunity.

D. N. Sidiropoulos, C. Rafie, B. J. Christmas, E. F. Davis-Marcisak, G. Sharma, E. Bigelow, A. Gupta, S. Yegnasubramanian, V. Stearns, R. M. Connolly, D. A. Gaykalova, L. T. Kagohara, E. M. Jaffee, E. J. Fertig, E. T. Roussos-Torres

The paper uses single-cell RNA-sequencing to show entinostat shifts tumor microenvironment cell states, reducing immunosuppression and enhancing immune checkpoint inhibitor responses in HER2+ breast tumors.

bioRxiv · Jan 29, 2021 · PreprintImmunology