Author

D. Ai

Justus-Liebig-Universität Gießen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Meinhardt· 2 shared S. Bhushan· 2 shared A. Chen· 1 shared B. Li· 1 shared C. Han· 1 shared C. Kantores· 1 shared C. Pleuger· 1 shared Christiane PleugeriD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

A. Meinhardt

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Depletion of CX3CR1+ macrophages results in disrupted functionality and immune surveillance within epididymis and testis

D. Ai, Linda Kreyling, María Agustina Battistone, Maia Lina Elizagaray, A. Chen, S. Bhushan, Monika Fijak, Martin Speckmann, G. Michel, Tara Procida‐Kowalski, Marek Bartkuhn, M. Sprang, Johannes U. Mayer, A. Meinhardt, Christiane Pleuger

This study shows that CX3CR1+ macrophages are essential for maintaining immune balance and epithelial integrity in the epididymis and testis, with their depletion leading to immune dysfunction and fertility issues.

Mucosal Immunology · Jan 31, 2026Peer-reviewedImmunology

Regulation of blood pressure by METTL3 via RUNX1b-eNOS pathway in endothelial cells

B. Li, Y. Zhang, X. Yang, M. Lan, Z. Yuan, S. Li, Y. Liu, C. Han, D. Ai, Y. Yang, Y. Zhu

This study shows METTL3 reduces blood pressure by stabilizing RUNX1b mRNA via m6A modification, increasing eNOS expression in endothelial cells.

bioRxiv · Dec 11, 2023 · PreprintCell Biology

The regional distribution of resident immune cells shapes distinct immunological environments along the murine epididymis

C. Pleuger, D. Ai, M. L. Hoppe, L. T. Winter, D. Bohnert, D. Karl, S. Guenther, S. Epelman, C. Kantores, M. Fijak, S. Ravens, R. Middendorff, J. U. Mayer, K. L. Loveland, M. P. Hedger, , A. Meinhardt

The paper identifies region-specific immune cell subsets in the murine epididymis using scRNA-seq, revealing distinct immunological environments along the duct.

bioRxiv · Jun 13, 2022Immunology