Author

D. D'souza

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Approach:statistical model· 2 Approach:benchmark study· 1

Frequent Co-Authors

S. Kim-Schulze· 3 shared T. Dawson· 3 shared A. H. Rahman· 2 shared A. Tabachnikova· 2 shared C. Chang· 2 shared D. Geanon· 2 shared E. Kenigsberg· 2 shared M. Buckup· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

S. Kim-Schulze

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Author profile →

4 papers

Recent·Most cited

Myeloid cell influx into the colonic epithelium is associated with disease severity and non-response to anti-Tumor Necrosis Factor Therapy in patients with Ulcerative Colitis.

D. Jha, Z. Al-Taie, A. Krek, S. T. Eshghi, A. Fantou, T. Laurent, M. Tankelevich, X. Cao, H. Meringer, A. Livanos, M. Tokuyama, F. Cossarini, A. Bourreille, R. Josien, R. Hou, , S. Mehandru

The paper identifies myeloid cell influx and epithelial cell perturbations in ulcerative colitis, linking them to disease severity and anti-TNF therapy non-response.

bioRxiv · Jun 2, 2023 · PreprintImmunology

Intratumoral mregDC and CXCL13 T helper niches enable local differentiation of CD8 T cells following PD-1 blockade

A. Magen, P. Hamon, N. Fiaschi, L. Troncoso, E. Humblin, D. D'souza, T. Dawson, M. D. Park, J. Kim, S. Hamel, M. Buckup, C. Chang, A. Tabachnikova, H. Schwartz, N. Malissen, , Merad

The paper identifies intratumoral niches involving mregDC and CXCL13+ Th cells that support CD8 T cell differentiation following PD-1 blockade in HCC patients.

bioRxiv · Jun 22, 2022 · PreprintImmunology

Shift of lung macrophage composition is associated with COVID-19 disease severity and recovery

S. T. Chen, M. D. Park, D. M. Del Valle, M. Buckup, A. Tabachnikova, N. W. Simons, K. Mouskas, B. Lee, D. Geanon, D. D'Souza, T. Dawson, R. Marvin, K. Nie, R. Thompson, Z. Zhao, , M. Merad

This study identifies shifts in lung macrophage composition linked to COVID-19 severity and recovery, suggesting therapeutic strategies targeting macrophage function.

bioRxiv · Jan 11, 2022 · PreprintImmunology

Multimodal Single-Cell Characterization of the Human Granulocyte Lineage

J. Qi, D. D'Souza, T. Dawson, D. Geanon, H. Stefanos, R. Marvin, L. Walker, A. H. Rahman

This study uses multi-modal CITE-seq to accurately characterize human granulocytes, showing higher transcript detection with BD Rhapsody compared to 10X Genomics.

bioRxiv · Jun 12, 2021 · PreprintImmunology