Author

D. Grotjahn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Madhavan· 1 shared A. Mehmood· 1 shared A. Mehrani· 1 shared B. A. Barad· 1 shared C. Cole· 1 shared D. Lyumkis· 1 shared D. O. Passos· 1 shared D. Park· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCell Biology

A. Madhavan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Secreted antigen A peptidoglycan hydrolase is essential for Enterococcus faecium cell separation and priming of immune checkpoint inhibitor cancer therapy

S. Klupt, K. T. Fam, X. Zhang, P. K. Chodisetti, A. Mehmood, T. Boyd, D. Grotjahn, D. Park, H. C. Hang

This study identifies SagA as essential for E. faecium growth, cell separation, and immune checkpoint inhibitor cancer therapy, showing its role in muropeptide production and NOD2 activation.

bioRxiv · Nov 19, 2023Microbiology

Overcoming Resolution Attenuation During Tilted Cryo-EM Data Collection

S. Aiyer, P. R. Baldwin, S. M. Tan, Z. Shan, J. Oh, A. Mehrani, M. E. Bowman, G. Louie, D. O. Passos, S. Đorđevic-Marquardt, M. Mietzsch, J. A. Hull, S. Hoshika, B. A. Barad, D. Grotjahn, , D. Lyumkis

This study improves cryo-EM data collection by reducing resolution attenuation during stage tilt, enabling isotropic map reconstruction of specimens with preferred orientations.

bioRxiv · Jul 14, 2023Biophysics

PERK Signaling Promotes Mitochondrial Elongation By Remodeling Membrane Phosphatidic Acid

V. Perea, C. Cole, J. Lebeau, V. Dolina, K. R. Baron, A. Madhavan, J. W. Kelly, D. Grotjahn, R. L. Wiseman

The paper shows PERK signaling promotes mitochondrial elongation by remodeling membrane phosphatidic acid during ER stress.

bioRxiv · Feb 23, 2022Cell Biology