Proteomic Analysis Reveals a PLK1-Dependent G2/M Degradation Program and Links PKA-AKAP2 to Cell Cycle Control
R. D. Mouery, C. Hsu, T. Bonacci…·M. Emanuele
The paper uses proteomics and PLK1 inhibition to identify proteins degraded at G2/M, showing PLK1's role in coordinating proteolysis via SCF ligases and linking AKAP2 to cell cycle control.