Frizzled-7 Identifies Platinum Tolerant Ovarian Cancer Cells Susceptible to Ferroptosis
Y. Wang, G. Zhao, S. Condello, H. Huang, H. Cardenas, E. Tanner, J.-J. Wei, Y. Ji, J. Li, Y. Tan, R. Davuluri, J.-X. Cheng, D. Matei
The paper identifies FZD7 as a marker of platinum-tolerant ovarian cancer cells that are susceptible to ferroptosis via the FZD7-β-catenin-Tp63-GPX4 pathway.
bioRxiv · May 28, 2020Cancer Biology